Detailed information NTG0737552

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: ODS73_RS06605
• Genome accession: NZ_CP107038
• Coordinates: 1293043..1293891 (-)
• Length: 282 a.a.
• NCBI ID: WP_057526442.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BM6001
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1288043..1298891

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ODS73_RS06585 (ODS73_06585)	-	1288399..1288758 (-)	360	WP_001237223.1	YbaN family protein	-
ODS73_RS06590 (ODS73_06590)	topA	1288864..1290951 (-)	2088	WP_000179644.1	type I DNA topoisomerase	-
ODS73_RS06595 (ODS73_06595)	-	1291118..1292161 (-)	1044	WP_001812883.1	TIGR00341 family protein	-
ODS73_RS06600 (ODS73_06600)	-	1292738..1292860 (+)	123	WP_001814242.1	hypothetical protein	-
ODS73_RS06605 (ODS73_06605)	dprA/cilB/dalA	1293043..1293891 (-)	849	WP_057526442.1	DNA-processing protein DprA	Machinery gene
ODS73_RS06610 (ODS73_06610)	-	1293987..1294676 (-)	690	WP_000643970.1	sugar phosphate nucleotidyltransferase	-
ODS73_RS06615 (ODS73_06615)	-	1294688..1295566 (-)	879	WP_000837618.1	DMT family transporter	-
ODS73_RS06620 (ODS73_06620)	licA	1295556..1296425 (-)	870	WP_000411215.1	choline kinase LicA	-
ODS73_RS06625 (ODS73_06625)	-	1296442..1297464 (-)	1023	WP_000609885.1	ribitol-5-phosphate dehydrogenase	-
ODS73_RS06630 (ODS73_06630)	-	1297469..1298176 (-)	708	WP_000638502.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31048.74 Da
• Isoelectric Point: 5.6729

>NTDB_id=737552 ODS73_RS06605 WP_057526442.1 1293043..1293891(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain BM6001]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRKPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=737552 ODS73_RS06605 WP_057526442.1 1293043..1293891(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain BM6001]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAAACCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGCTCTAAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.291	100	0.993
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis SK321	97.163	100	0.972
dprA	Streptococcus mutans UA159	63.571	99.291	0.631
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.456	100	0.376
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362