Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   C11O2_RS05085 Genome accession   NZ_AP019548
Coordinates   982817..983005 (-) Length   62 a.a.
NCBI ID   WP_011285559.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 10-85     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 975233..993800 982817..983005 within 0


Gene organization within MGE regions


Location: 975233..993800
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C11O2_RS05050 (A85_09130) pfkA 975233..976246 (-) 1014 WP_010922375.1 6-phosphofructokinase -
  C11O2_RS05055 (A85_09140) - 976326..979436 (-) 3111 WP_010922376.1 DNA polymerase III subunit alpha -
  C11O2_RS05060 (A85_09150) - 979621..979992 (+) 372 WP_010922377.1 GntR family transcriptional regulator -
  C11O2_RS05065 (A85_09160) - 979992..980690 (+) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  C11O2_RS05070 (A85_09170) - 980700..981485 (+) 786 WP_010922378.1 hypothetical protein -
  C11O2_RS05075 (A85_09180) - 981612..982226 (-) 615 WP_011285558.1 TVP38/TMEM64 family protein -
  C11O2_RS05085 (A85_09190) prx 982817..983005 (-) 189 WP_011285559.1 hypothetical protein Regulator
  C11O2_RS05090 (A85_09200) speA 983225..983980 (+) 756 WP_011285560.1 streptococcal pyrogenic exotoxin SpeA -
  C11O2_RS05095 (A85_09210) - 984102..984761 (-) 660 WP_009880240.1 hypothetical protein -
  C11O2_RS05100 (A85_09220) - 984761..984982 (-) 222 WP_009880241.1 hypothetical protein -
  C11O2_RS05105 (A85_09230) - 984992..985765 (-) 774 WP_011054795.1 hypothetical protein -
  C11O2_RS05110 (A85_09240) - 985776..986378 (-) 603 WP_011054796.1 hypothetical protein -
  C11O2_RS05115 (A85_09250) - 986390..987154 (-) 765 WP_011285561.1 CHAP domain-containing protein -
  C11O2_RS05120 (A85_09260) - 987480..987689 (+) 210 WP_011017885.1 hypothetical protein -
  C11O2_RS05125 (A85_09270) - 987799..987999 (-) 201 WP_002992770.1 helix-turn-helix domain-containing protein -
  C11O2_RS05130 (A85_09280) - 988073..988459 (+) 387 WP_011054589.1 hypothetical protein -
  C11O2_RS05135 (A85_09290) - 988448..988657 (-) 210 WP_011284881.1 hypothetical protein -
  C11O2_RS05140 (A85_09300) - 988711..989310 (+) 600 WP_011284882.1 hypothetical protein -
  C11O2_RS05145 (A85_09310) - 989340..989498 (-) 159 WP_011285583.1 hypothetical protein -
  C11O2_RS05150 (A85_09320) - 989855..990679 (+) 825 WP_011285584.1 XRE family transcriptional regulator -
  C11O2_RS05155 (A85_09330) - 990715..991608 (+) 894 WP_011285585.1 P63C domain-containing protein -
  C11O2_RS05160 (A85_09340) - 991729..992817 (+) 1089 WP_011054595.1 site-specific integrase -
  C11O2_RS05165 (A85_09350) - 993180..993800 (+) 621 WP_002989605.1 DUF3862 domain-containing protein -

Sequence

Protein


Download         Length: 62 a.a.        Molecular weight: 7290.41 Da        Isoelectric Point: 4.3313

>NTDB_id=72883 C11O2_RS05085 WP_011285559.1 982817..983005(-) (prx) [Streptococcus pyogenes strain 10-85]
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=72883 C11O2_RS05085 WP_011285559.1 982817..983005(-) (prx) [Streptococcus pyogenes strain 10-85]
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGATGATGAAGTTGTGACGGTAGAGAGAGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

95.161

0.952
  prx Streptococcus pyogenes MGAS315

79.032

100

0.79
  prx Streptococcus pyogenes MGAS8232

76.271

95.161

0.726
  prx Streptococcus pyogenes MGAS315

76.271

95.161

0.726
  prx Streptococcus pyogenes MGAS315

74.576

95.161

0.71
  prx Streptococcus pyogenes MGAS315

69.492

95.161

0.661
  prx Streptococcus pyogenes MGAS315

82.927

66.129

0.548

Multiple sequence alignment