NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	NX050_RS03565	Genome accession	NZ_CP103456
Coordinates	696410..697003 (-)	Length	197 a.a.
NCBI ID	WP_003228214.1	Uniprot ID	A0A199WEF2
Organism	Bacillus subtilis strain PN176 (HK176)
Function	degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 691410..702003

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NX050_RS03550 (NX050_03550)	mdxK	691725..693998 (+)	2274	WP_014480985.1	maltose phosphorylase	-
NX050_RS03555 (NX050_03555)	malL	693991..695676 (+)	1686	WP_033881298.1	oligo-1,6-glucosidase	-
NX050_RS03560 (NX050_03560)	pgmB	695673..696347 (+)	675	WP_014480982.1	beta-phosphoglucomutase	-
NX050_RS03565 (NX050_03565)	clpP	696410..697003 (-)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
NX050_RS03575 (NX050_03575)	-	697549..698538 (+)	990	WP_014480981.1	tyrosine-type recombinase/integrase	-
NX050_RS03580 (NX050_03580)	-	698697..699428 (+)	732	WP_041516560.1	helix-turn-helix domain-containing protein	-
NX050_RS03585 (NX050_03585)	-	699459..699641 (-)	183	WP_033881294.1	hypothetical protein	-
NX050_RS03590 (NX050_03590)	-	699701..699934 (-)	234	WP_033881293.1	helix-turn-helix transcriptional regulator	-
NX050_RS03595 (NX050_03595)	-	700523..700858 (+)	336	WP_031601018.1	hypothetical protein	-
NX050_RS03600 (NX050_03600)	-	701060..701287 (-)	228	WP_306306790.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

Download Length: 197 a.a. Molecular weight: 21682.00 Da Isoelectric Point: 4.9416

                                >NTDB_id=722856 NX050_RS03565 WP_003228214.1 696410..697003(-) (clpP) [Bacillus subtilis strain PN176 (HK176)]

MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT

MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ

PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

Download Length: 594 bp

                                >NTDB_id=722856 NX050_RS03565 WP_003228214.1 696410..697003(-) (clpP) [Bacillus subtilis strain PN176 (HK176)]

ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA

TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG

AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC

ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCATCAATGGGCGCTTTCCTGCTTGCAGCCGG

CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA

CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAACTAAACAAAGTCCTTGCTGAACGTACTGGCCAG

CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA

CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A199WEF2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538

Detailed information NTG0722856