Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   PVK48_RS05390 Genome accession   NZ_CP118307
Coordinates   1055294..1055482 (-) Length   62 a.a.
NCBI ID   WP_011285559.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 20200554     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 1050294..1060482
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVK48_RS05365 (PVK48_05315) - 1052092..1052463 (+) 372 WP_346393437.1 GntR family transcriptional regulator -
  PVK48_RS05370 (PVK48_05320) - 1052463..1053161 (+) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  PVK48_RS05375 (PVK48_05325) - 1053171..1053956 (+) 786 WP_002989610.1 hypothetical protein -
  PVK48_RS05380 (PVK48_05330) - 1054089..1054703 (-) 615 WP_002989607.1 TVP38/TMEM64 family protein -
  PVK48_RS05390 (PVK48_05340) prx 1055294..1055482 (-) 189 WP_011285559.1 hypothetical protein Regulator
  PVK48_RS05395 (PVK48_05345) speA 1055702..1056457 (+) 756 WP_011285560.1 streptococcal pyrogenic exotoxin SpeA -
  PVK48_RS05400 (PVK48_05350) - 1056579..1057238 (-) 660 WP_009880240.1 hypothetical protein -
  PVK48_RS05405 (PVK48_05355) - 1057238..1057459 (-) 222 WP_009880241.1 hypothetical protein -
  PVK48_RS05410 (PVK48_05360) - 1057469..1058242 (-) 774 WP_011054795.1 hypothetical protein -
  PVK48_RS05415 (PVK48_05365) - 1058253..1058855 (-) 603 WP_011054796.1 hypothetical protein -
  PVK48_RS05420 (PVK48_05370) - 1058867..1059631 (-) 765 WP_011285561.1 CHAP domain-containing protein -
  PVK48_RS05425 (PVK48_05375) - 1059633..1059965 (-) 333 WP_011285562.1 phage holin -
  PVK48_RS05430 (PVK48_05380) - 1059965..1060288 (-) 324 WP_015055952.1 hypothetical protein -
  PVK48_RS05435 (PVK48_05385) - 1060302..1060424 (-) 123 WP_015055953.1 hypothetical protein -

Sequence


Protein


Download         Length: 62 a.a.        Molecular weight: 7290.41 Da        Isoelectric Point: 4.3313

>NTDB_id=721736 PVK48_RS05390 WP_011285559.1 1055294..1055482(-) (prx) [Streptococcus pyogenes strain 20200554]
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=721736 PVK48_RS05390 WP_011285559.1 1055294..1055482(-) (prx) [Streptococcus pyogenes strain 20200554]
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGATGATGAAGTTGTGACGGTAGAGAGAGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

95.161

0.952

  prx Streptococcus pyogenes MGAS315

79.032

100

0.79

  prx Streptococcus pyogenes MGAS8232

76.271

95.161

0.726

  prx Streptococcus pyogenes MGAS315

76.271

95.161

0.726

  prx Streptococcus pyogenes MGAS315

74.576

95.161

0.71

  prx Streptococcus pyogenes MGAS315

69.492

95.161

0.661

  prx Streptococcus pyogenes MGAS315

82.927

66.129

0.548