Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   PUW74_RS00405 Genome accession   NZ_CP118080
Coordinates   63732..64640 (+) Length   302 a.a.
NCBI ID   WP_000912095.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain VSI14     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 58732..69640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW74_RS00385 (PUW74_00385) purE 59249..59737 (+) 489 WP_001182531.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  PUW74_RS00390 (PUW74_00390) purK 59724..60815 (+) 1092 WP_001084008.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  PUW74_RS00395 (PUW74_00395) - 60868..62259 (+) 1392 WP_001079797.1 hypothetical protein -
  PUW74_RS00400 (PUW74_00400) purB 62281..63579 (+) 1299 WP_000572890.1 adenylosuccinate lyase -
  PUW74_RS00405 (PUW74_00405) comR 63732..64640 (+) 909 WP_000912095.1 XRE family transcriptional regulator Regulator
  PUW74_RS00410 (PUW74_00410) ruvB 64841..65839 (+) 999 WP_000196633.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  PUW74_RS00415 (PUW74_00415) - 65991..66428 (+) 438 WP_000754818.1 low molecular weight protein-tyrosine-phosphatase -
  PUW74_RS00420 (PUW74_00420) - 66435..66815 (+) 381 WP_000787702.1 membrane protein -
  PUW74_RS00425 (PUW74_00425) - 66812..68590 (+) 1779 WP_001220907.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 302 a.a.        Molecular weight: 35727.11 Da        Isoelectric Point: 5.5329

>NTDB_id=721167 PUW74_RS00405 WP_000912095.1 63732..64640(+) (comR) [Streptococcus agalactiae strain VSI14]
MLKHFGSKVRKFRESQQVTREEFCGDESELSVRQLARIEAGESVPNLSKAHYIARNLGVSLDSLTAGASLELSKKYKELK
YLILRTPTYNDTDRLDLIEKYLDEIYLNFYDDLPEDEKIAIESIQSSLDIYISKSHHFGDDLIREYMNQIKRKKIYSIND
LLIIKLWQYKITASRYDPNIFKIDTFIGTIDKLLNQVKVLSIENLFLLRDVLIYSLGILFILAEYQQIENIINTLNDILI
KTQDFQKRPIIDMFEWKYQLFYKENREVAKRKYQESTLFAQLIGDQVLVTQLKEEWKADYIE

Nucleotide


Download         Length: 909 bp        

>NTDB_id=721167 PUW74_RS00405 WP_000912095.1 63732..64640(+) (comR) [Streptococcus agalactiae strain VSI14]
ATGTTAAAACATTTTGGTAGTAAAGTAAGGAAGTTTAGGGAATCTCAACAGGTGACACGAGAAGAATTTTGTGGCGATGA
ATCAGAGTTATCGGTCCGACAGCTGGCTCGGATTGAAGCAGGAGAATCTGTTCCAAATTTATCTAAGGCGCATTATATCG
CTAGAAATCTAGGAGTTAGTTTAGATTCCTTAACAGCAGGAGCGAGTTTAGAACTGTCAAAAAAATATAAGGAATTAAAG
TATCTTATATTAAGGACGCCTACCTACAATGATACAGATAGACTTGATTTGATTGAAAAATATCTAGATGAGATTTATTT
AAATTTCTATGATGATTTACCTGAAGATGAAAAAATAGCAATTGAGTCCATACAAAGTTCTTTAGATATTTATATTTCTA
AAAGCCATCATTTTGGAGATGACCTGATTAGGGAATACATGAATCAAATTAAACGAAAAAAGATTTACTCTATCAATGAC
TTACTTATAATTAAACTATGGCAATATAAGATTACTGCTAGCAGGTATGATCCCAATATTTTTAAAATAGATACATTTAT
TGGTACTATAGATAAGTTGCTTAATCAAGTAAAGGTATTATCAATTGAAAACCTGTTTTTATTAAGGGATGTCCTCATTT
ATTCGTTAGGTATATTGTTTATATTAGCTGAATATCAGCAAATAGAAAATATAATAAATACTCTAAATGATATTTTAATA
AAAACTCAGGATTTTCAAAAGAGGCCAATAATAGATATGTTCGAATGGAAATATCAGTTGTTTTATAAAGAAAATAGGGA
AGTGGCTAAAAGAAAGTATCAGGAATCAACTCTTTTTGCTCAATTAATTGGCGATCAAGTTTTAGTTACACAGCTAAAAG
AGGAATGGAAAGCAGACTATATAGAATAA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(74-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

45.151

99.007

0.447
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

45.296

95.033

0.43
  comR Streptococcus pyogenes MGAS315

43.478

99.007

0.43
  comR Streptococcus pyogenes MGAS8232

41.914

100

0.421
  comR Streptococcus suis P1/7

42.424

98.344

0.417
  comR Streptococcus suis 05ZYH33

42.424

98.344

0.417
  comR Streptococcus suis D9

38.384

98.344

0.377