Detailed information NTG0720520

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: NW979_RS12910
• Genome accession: NZ_CP102959
• Coordinates: 2646219..2647106 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 12-G-51
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2641219..2652106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NW979_RS12880 (NW979_12880)	-	2641238..2641330 (+)	93	WP_010956583.1	hypothetical protein	-
NW979_RS12885 (NW979_12885)	-	2641438..2641935 (-)	498	WP_001065268.1	glutathione peroxidase	-
NW979_RS12890 (NW979_12890)	-	2641945..2642205 (-)	261	WP_001789910.1	hypothetical protein	-
NW979_RS12895 (NW979_12895)	-	2642587..2642700 (-)	114	WP_011447078.1	hypothetical protein	-
NW979_RS12900 (NW979_12900)	-	2643359..2645359 (-)	2001	WP_071008756.1	ABC transporter permease	-
NW979_RS12905 (NW979_12905)	-	2645356..2646111 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
NW979_RS12910 (NW979_12910)	braS	2646219..2647106 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
NW979_RS12915 (NW979_12915)	braR	2647117..2647782 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
NW979_RS12920 (NW979_12920)	-	2647808..2648008 (-)	201	WP_000604727.1	hypothetical protein	-
NW979_RS12925 (NW979_12925)	-	2648206..2649630 (+)	1425	WP_258413571.1	alkaline phosphatase	-
NW979_RS13365	-	2649690..2649791 (-)	102	WP_000731976.1	SE2200 family small protein	-
NW979_RS12935 (NW979_12935)	-	2649913..2650368 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
NW979_RS12940 (NW979_12940)	-	2650613..2651374 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=720520 NW979_RS12910 WP_000143420.1 2646219..2647106(-) (braS) [Staphylococcus aureus strain 12-G-51]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=720520 NW979_RS12910 WP_000143420.1 2646219..2647106(-) (braS) [Staphylococcus aureus strain 12-G-51]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993