Detailed information NTG0719049

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: NWO26_RS08680
• Genome accession: NZ_CP102797
• Coordinates: 1670845..1671744 (+)
• Length: 299 a.a.
• NCBI ID: WP_113870435.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST057-1
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 1665845..1676744

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWO26_RS08660	trkA	1666981..1668330 (-)	1350	WP_014621137.1	Trk system potassium transporter TrkA	-
NWO26_RS08665	-	1668590..1669129 (+)	540	WP_372585740.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
NWO26_RS08670	-	1669440..1669997 (+)	558	WP_011680718.1	ECF transporter S component	-
NWO26_RS08675	-	1670000..1670650 (+)	651	WP_113870436.1	phosphatase PAP2 family protein	-
NWO26_RS08680	comR	1670845..1671744 (+)	900	WP_113870435.1	helix-turn-helix domain-containing protein	Regulator
NWO26_RS08685	-	1671982..1672413 (+)	432	Protein_1657	cysteine peptidase family C39 domain-containing protein	-
NWO26_RS08690	-	1672443..1673108 (+)	666	Protein_1658	ABC transporter transmembrane domain-containing protein	-
NWO26_RS08695	comA	1673181..1673390 (+)	210	WP_002946147.1	hypothetical protein	Regulator
NWO26_RS08700	-	1673445..1674013 (+)	569	Protein_1660	ATP-binding cassette domain-containing protein	-
NWO26_RS08705	-	1674121..1674438 (+)	318	WP_011225454.1	DUF805 domain-containing protein	-
NWO26_RS08710	-	1674401..1674685 (-)	285	WP_014727318.1	hypothetical protein	-
NWO26_RS08715	-	1674925..1675227 (-)	303	WP_231910735.1	hypothetical protein	-
NWO26_RS08720	-	1675451..1675822 (-)	372	WP_224103195.1	hypothetical protein	-
NWO26_RS08725	-	1676227..1676742 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35271.66 Da
• Isoelectric Point: 5.0061

>NTDB_id=719049 NWO26_RS08680 WP_113870435.1 1670845..1671744(+) (comR) [Streptococcus thermophilus strain ST057-1]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
LKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=719049 NWO26_RS08680 WP_113870435.1 1670845..1671744(+) (comR) [Streptococcus thermophilus strain ST057-1]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
TTGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.331	100	0.993
comR	Streptococcus thermophilus LMD-9	98.662	100	0.987
comR	Streptococcus salivarius strain HSISS4	94.649	100	0.946
comR	Streptococcus salivarius SK126	93.98	100	0.94
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.472	100	0.415