Detailed information NTG0718762

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: NWE21_RS07335
• Genome accession: NZ_CP102748
• Coordinates: 1475163..1475753 (-)
• Length: 196 a.a.
• NCBI ID: WP_002937303.1
• Uniprot ID: A0A0K2E545
• Organism: Streptococcus suis strain Transconjugant cSFJ45
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1470163..1480753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWE21_RS07310 (NWE21_07320)	-	1470647..1471411 (-)	765	WP_002937291.1	ABC transporter ATP-binding protein	-
NWE21_RS07315 (NWE21_07325)	-	1471411..1472358 (-)	948	WP_002937293.1	branched-chain amino acid ABC transporter permease	-
NWE21_RS07320 (NWE21_07330)	-	1472361..1473248 (-)	888	WP_012027482.1	branched-chain amino acid ABC transporter permease	-
NWE21_RS07325 (NWE21_07335)	-	1473464..1474633 (-)	1170	WP_012775268.1	ABC transporter substrate-binding protein	-
NWE21_RS07330 (NWE21_07340)	-	1474764..1475036 (-)	273	WP_002937299.1	YlbG family protein	-
NWE21_RS07335 (NWE21_07345)	clpP	1475163..1475753 (-)	591	WP_002937303.1	ATP-dependent Clp protease proteolytic subunit	Regulator
NWE21_RS07340 (NWE21_07350)	upp	1475870..1476499 (-)	630	WP_012027487.1	uracil phosphoribosyltransferase	-
NWE21_RS07345 (NWE21_07355)	-	1476579..1478195 (-)	1617	WP_012027489.1	glycoside hydrolase family 13 protein	-
NWE21_RS07350 (NWE21_07360)	gtfA	1478268..1479716 (-)	1449	WP_012027490.1	sucrose phosphorylase	-
NWE21_RS07355 (NWE21_07365)	-	1479787..1480617 (-)	831	WP_002937312.1	carbohydrate ABC transporter permease	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21494.74 Da
• Isoelectric Point: 5.7110

>NTDB_id=718762 NWE21_RS07335 WP_002937303.1 1475163..1475753(-) (clpP) [Streptococcus suis strain Transconjugant cSFJ45]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGTAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKILADNSGK
TVKQIHKDAERDYWMSAEETLAYGFIDQIMDNTKVK

Nucleotide

• Length: 591 bp

>NTDB_id=718762 NWE21_RS07335 WP_002937303.1 1475163..1475753(-) (clpP) [Streptococcus suis strain Transconjugant cSFJ45]
ATGATTCCAGTAGTTATTGAACAAACTAGCCGTGGTGAGCGTTCTTATGATATTTACTCACGCCTTTTGAAAGACCGTAT
TATCATGTTGACAGGACCAGTTGAGGACAACATGGCAAACTCTATCATTGCACAATTGCTTTTCCTTGATGCCCAAGACC
CTACAAAGGATATTTACCTCTATGTTAATACGCCAGGAGGATCGGTGTCAGCAGGTCTTGCCATTGTAGACACGATGAAT
TTCATTAAAGCTGATGTTCAAACCATCGTTATGGGAACAGCTGCGAGCATGGGAACCATCATTGCATCAAGCGGTGCCAA
GGGCAAACGTTTCATGTTGCCAAATGCAGAGTACATGATTCACCAGCCAATGGGTGGAACTGGTGGTGGTACTCAGCAAA
CAGATATGGCTATTGCTGCAGAACACCTATTAAAAACACGTAATAAGCTAGAAAAAATCTTGGCAGACAACTCAGGTAAG
ACAGTCAAGCAAATCCACAAGGATGCGGAACGTGATTACTGGATGTCAGCTGAAGAAACCTTGGCTTACGGATTTATTGA
CCAGATTATGGACAATACAAAAGTCAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A0K2E545

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes JRS4	92.347	100	0.923
clpP	Streptococcus pyogenes MGAS315	92.347	100	0.923
clpP	Streptococcus mutans UA159	90.306	100	0.903
clpP	Streptococcus pneumoniae R6	88.776	100	0.888
clpP	Streptococcus pneumoniae Rx1	88.776	100	0.888
clpP	Streptococcus pneumoniae D39	88.776	100	0.888
clpP	Streptococcus pneumoniae TIGR4	88.776	100	0.888
clpP	Streptococcus thermophilus LMG 18311	88.776	100	0.888
clpP	Streptococcus thermophilus LMD-9	88.776	100	0.888
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	84.184	100	0.842
clpP	Lactococcus lactis subsp. cremoris KW2	83.673	100	0.837
clpP	Bacillus subtilis subsp. subtilis str. 168	58.163	100	0.582
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.549	98.469	0.577