Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   NWE22_RS03410 Genome accession   NZ_CP102747
Coordinates   656505..657209 (+) Length   234 a.a.
NCBI ID   WP_024391260.1    Uniprot ID   A0A9X4MIJ1
Organism   Streptococcus parasuis strain SFJ45     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 651505..662209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS03390 (NWE22_03390) - 653317..653976 (-) 660 WP_171988525.1 amino acid ABC transporter permease -
  NWE22_RS03395 (NWE22_03395) - 653991..654689 (-) 699 WP_172036401.1 amino acid ABC transporter permease -
  NWE22_RS03400 (NWE22_03400) - 654704..655543 (-) 840 WP_277745600.1 transporter substrate-binding domain-containing protein -
  NWE22_RS03405 (NWE22_03405) - 655553..656314 (-) 762 WP_277745601.1 amino acid ABC transporter ATP-binding protein -
  NWE22_RS03410 (NWE22_03410) micA 656505..657209 (+) 705 WP_024391260.1 response regulator YycF Regulator
  NWE22_RS03415 (NWE22_03415) micB 657202..658551 (+) 1350 WP_277745602.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NWE22_RS03420 (NWE22_03420) vicX 658558..659361 (+) 804 WP_171988530.1 MBL fold metallo-hydrolase Regulator
  NWE22_RS03425 (NWE22_03425) pbp2b 659640..661712 (+) 2073 WP_171988531.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26727.72 Da        Isoelectric Point: 4.8061

>NTDB_id=718690 NWE22_RS03410 WP_024391260.1 656505..657209(+) (micA) [Streptococcus parasuis strain SFJ45]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALDIFEAEFPDIVILDLMLPEIDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQGAVESSGTPELVIGDLVIVPDAFVAKKHGKELELT
HREFELLYHLAKHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYFIKAYD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=718690 NWE22_RS03410 WP_024391260.1 656505..657209(+) (micA) [Streptococcus parasuis strain SFJ45]
ATGAAGAAAATTTTAATTGTTGATGATGAGAAACCAATCTCGGATATTATTAAGTTCAATATGACACGTGAAGGATATGA
GGTAGTTACTGCGTTTGATGGACGTGAGGCGCTTGATATTTTTGAAGCAGAGTTTCCAGACATTGTTATTTTAGATTTAA
TGCTTCCAGAAATAGATGGATTAGAAGTAGCACGGACGATTCGAAAAACAAGTAATGTTCCTATTTTAATGTTGTCAGCT
AAAGATAGTGAGTTTGATAAAGTTATTGGGCTTGAAATTGGTGCGGATGACTATGTGACAAAGCCATTCTCAAACCGTGA
ATTACAGGCGCGTGTAAAAGCTCTTCTTCGTCGAAGTGAATTGGCTGAGACGCAAGGAGCAGTTGAATCATCTGGTACTC
CAGAATTGGTAATCGGTGATTTGGTAATTGTTCCAGATGCTTTTGTAGCTAAGAAACATGGAAAAGAACTTGAACTAACA
CACCGTGAATTTGAATTATTGTATCATTTGGCCAAGCACATTGGGCAAGTCATGACGCGAGAGCATCTACTTGAGACTGT
TTGGGGATATGATTATTTTGGAGATGTACGTACTGTGGACGTGACGGTTCGACGCTTGCGTGAAAAAATTGAAGACACTC
CAAGTCGTCCGGAATATATCTTGACACGCAGGGGAGTAGGTTATTTTATAAAAGCTTATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

84.416

98.718

0.833
  vicR Streptococcus mutans UA159

80.851

100

0.812
  covR Streptococcus salivarius strain HSISS4

43.29

98.718

0.427
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.043

98.291

0.423
  scnR Streptococcus mutans UA159

36.709

100

0.372