Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   NWE22_RS03415 Genome accession   NZ_CP102747
Coordinates   657202..658551 (+) Length   449 a.a.
NCBI ID   WP_277745602.1    Uniprot ID   -
Organism   Streptococcus parasuis strain SFJ45     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 652202..663551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE22_RS03390 (NWE22_03390) - 653317..653976 (-) 660 WP_171988525.1 amino acid ABC transporter permease -
  NWE22_RS03395 (NWE22_03395) - 653991..654689 (-) 699 WP_172036401.1 amino acid ABC transporter permease -
  NWE22_RS03400 (NWE22_03400) - 654704..655543 (-) 840 WP_277745600.1 transporter substrate-binding domain-containing protein -
  NWE22_RS03405 (NWE22_03405) - 655553..656314 (-) 762 WP_277745601.1 amino acid ABC transporter ATP-binding protein -
  NWE22_RS03410 (NWE22_03410) micA 656505..657209 (+) 705 WP_024391260.1 response regulator YycF Regulator
  NWE22_RS03415 (NWE22_03415) micB 657202..658551 (+) 1350 WP_277745602.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NWE22_RS03420 (NWE22_03420) vicX 658558..659361 (+) 804 WP_171988530.1 MBL fold metallo-hydrolase Regulator
  NWE22_RS03425 (NWE22_03425) pbp2b 659640..661712 (+) 2073 WP_171988531.1 penicillin-binding protein PBP2B -
  NWE22_RS03430 (NWE22_03430) recR 661721..662317 (+) 597 WP_002935848.1 recombination mediator RecR -
  NWE22_RS03435 (NWE22_03435) - 662426..663472 (+) 1047 WP_277745603.1 D-alanine--D-alanine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51024.34 Da        Isoelectric Point: 4.5346

>NTDB_id=718691 NWE22_RS03415 WP_277745602.1 657202..658551(+) (micB) [Streptococcus parasuis strain SFJ45]
MINQLRYLITTAEFWFVVILVGFLIALTVLLIENYRDNKQIQLLNKKVGALIDGNYSDVLDLRGSPEITEMANSLNDLSE
VIRLTHDHLEQEKIRLSSILSYMSDGVIATDRIGRIIMVNDMAQKQLGLKDHEQEQYFLLDVLELQDQYSLRELLSQTPE
IVLEKVNENQELLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGEMDVELINFTAFITFILNRFDQMKNSDVGKTYAIIRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGNITFSMKTTDSQLILSISDEGLGIPKADLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWEEVAEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=718691 NWE22_RS03415 WP_277745602.1 657202..658551(+) (micB) [Streptococcus parasuis strain SFJ45]
ATGATTAATCAATTACGCTATCTAATTACAACAGCTGAATTTTGGTTTGTTGTTATTTTGGTCGGCTTTCTAATTGCGTT
GACAGTATTGTTGATAGAAAACTATCGTGACAATAAGCAGATTCAATTACTCAATAAAAAAGTTGGCGCCTTGATAGATG
GTAATTACTCTGATGTATTGGATTTGCGAGGAAGTCCAGAGATTACTGAAATGGCAAATTCACTGAATGATTTGTCAGAA
GTAATCCGTTTAACGCACGATCACCTAGAACAAGAAAAAATCCGGCTCAGTTCCATTCTTTCCTACATGAGTGATGGAGT
CATTGCTACAGATCGTATTGGCCGAATTATCATGGTCAATGATATGGCGCAGAAACAACTGGGGTTAAAAGATCATGAAC
AGGAGCAATATTTTTTACTTGATGTTCTAGAACTTCAAGACCAATATAGTCTGCGTGAGTTGTTATCTCAAACACCTGAA
ATCGTCTTAGAAAAAGTTAATGAGAATCAAGAATTACTGACCTTACGAGCTAATTTTGCAACGATTAGGAGTGAAAGTGG
GCTCATATCAGGGTTGGTTGTTGTCCTACATGATATGACGGAGCAGGCCAAGGAGGAACGTGAGCGCAGACTGTTTGTTT
CTAATGTCAGTCACGAATTGCGTACACCGTTGACCTCGGTTAAATCATATTTGGAAGCCTTGGATGAGGGAGCTCTGACT
GAATCGGTTGCCCCAAGTTTTGTCAAGGTATCCTTAGATGAAACCAACCGGATGATGCGGATGATTACAGATCTTTTAAG
TTTATCTCGCATTGATAATCAGGTTGGAGAGATGGATGTAGAGTTAATCAATTTTACAGCCTTTATCACTTTTATCTTGA
ATCGCTTTGATCAGATGAAGAATTCTGATGTTGGTAAGACCTACGCTATTATTCGTGATTACCAGATTAGTCCAATTTGG
GTTGAAATTGATACCGATAAGATGACGCAGGTACTGGATAATATTTTGAATAATGCTATCAAGTATTCTCCAGATGGGGG
AAACATTACCTTTAGTATGAAAACGACAGATAGTCAGCTTATTCTTTCTATTTCAGATGAAGGTTTGGGAATTCCTAAAG
CTGATTTACCTAAAATATTTGACCGTTTCTATCGAGTTGATAAAGCGCGTTCGAGAGCCCAAGGAGGCACAGGTTTAGGT
TTGGCGATTGCAAAAGAGATTGTAAAGCAACACAAAGGATTCATTTGGGCTAAAAGTGAGTATGGACATGGTTCGACATT
TACGATTGTCTTACCATATAGTAAGGATATTGCACTGGATGAGTGGGAAGAGGTTGCTGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.037

97.105

0.67
  vicK Streptococcus mutans UA159

69.479

89.755

0.624