Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NUU05_RS09070 Genome accession   NZ_CP102538
Coordinates   1733686..1734585 (-) Length   299 a.a.
NCBI ID   WP_011680720.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TH-4     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1728686..1739585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NUU05_RS09025 (NUU05_08990) - 1728687..1729202 (-) 516 WP_002949547.1 AmiS/UreI family transporter -
  NUU05_RS09030 (NUU05_08995) - 1729608..1729979 (+) 372 WP_224103195.1 hypothetical protein -
  NUU05_RS09035 (NUU05_09000) - 1730203..1730505 (+) 303 WP_224103194.1 hypothetical protein -
  NUU05_RS09045 (NUU05_09010) - 1730998..1731186 (-) 189 WP_224103239.1 hypothetical protein -
  NUU05_RS09050 (NUU05_09015) - 1731417..1731985 (-) 569 Protein_1717 ATP-binding cassette domain-containing protein -
  NUU05_RS09055 (NUU05_09020) comA 1732040..1732249 (-) 210 WP_002946147.1 hypothetical protein Regulator
  NUU05_RS09060 (NUU05_09025) comA 1732592..1732882 (-) 291 WP_194238295.1 ABC transporter transmembrane domain-containing protein Regulator
  NUU05_RS09065 (NUU05_09030) - 1732867..1733511 (-) 645 Protein_1720 cysteine peptidase family C39 domain-containing protein -
  NUU05_RS09070 (NUU05_09035) comR 1733686..1734585 (-) 900 WP_011680720.1 helix-turn-helix domain-containing protein Regulator
  NUU05_RS09075 (NUU05_09040) - 1734780..1735430 (-) 651 WP_011680719.1 phosphatase PAP2 family protein -
  NUU05_RS09080 (NUU05_09045) - 1735433..1735990 (-) 558 WP_011680718.1 ECF transporter S component -
  NUU05_RS09085 (NUU05_09050) - 1736301..1736840 (-) 540 WP_372585740.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  NUU05_RS09090 (NUU05_09055) trkA 1737099..1738448 (+) 1350 WP_011225444.1 Trk system potassium transporter TrkA -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35271.71 Da        Isoelectric Point: 5.1073

>NTDB_id=717654 NUU05_RS09070 WP_011680720.1 1733686..1734585(-) (comR) [Streptococcus thermophilus strain TH-4]
MNLKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIVFASVLEDSVLEESIKAGKLADGL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=717654 NUU05_RS09070 WP_011680720.1 1733686..1734585(-) (comR) [Streptococcus thermophilus strain TH-4]
TTGAACTTAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTTTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAGTGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

Helix-turn-helix (HTH_3)

(11-66)

ComR tetratricopeptide (ComR_TPR)

(75-292)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus thermophilus LMD-9

100

100

1
  comR Streptococcus thermophilus LMG 18311

99.331

100

0.993
  comR Streptococcus salivarius strain HSISS4

94.649

100

0.946
  comR Streptococcus salivarius SK126

93.98

100

0.94
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

42.14

100

0.421
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

41.472

100

0.415