Detailed information NTG0717649

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: NUU05_RS08670
• Genome accession: NZ_CP102538
• Coordinates: 1658311..1658901 (-)
• Length: 196 a.a.
• NCBI ID: WP_002949732.1
• Uniprot ID: Q5M5U4
• Organism: Streptococcus thermophilus strain TH-4
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1653311..1663901

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUU05_RS08640 (NUU05_08605)	-	1653520..1654284 (-)	765	WP_002949740.1	ABC transporter ATP-binding protein	-
NUU05_RS08645 (NUU05_08610)	-	1654287..1655237 (-)	951	WP_011225510.1	branched-chain amino acid ABC transporter permease	-
NUU05_RS08650 (NUU05_08615)	-	1655241..1656125 (-)	885	WP_011225509.1	branched-chain amino acid ABC transporter permease	-
NUU05_RS08655 (NUU05_08620)	-	1656169..1657344 (-)	1176	WP_011680765.1	ABC transporter substrate-binding protein	-
NUU05_RS08660 (NUU05_08625)	-	1657501..1657782 (-)	282	WP_002949736.1	YlbG family protein	-
NUU05_RS08665 (NUU05_08630)	-	1657775..1658224 (-)	450	WP_011680764.1	YlbF family regulator	-
NUU05_RS08670 (NUU05_08635)	clpP	1658311..1658901 (-)	591	WP_002949732.1	ATP-dependent Clp protease proteolytic subunit	Regulator
NUU05_RS08675 (NUU05_08640)	upp	1659039..1659668 (-)	630	WP_002946740.1	uracil phosphoribosyltransferase	-
NUU05_RS08680 (NUU05_08645)	-	1659798..1660073 (-)	276	WP_011680763.1	hypothetical protein	-
NUU05_RS08685 (NUU05_08650)	-	1660114..1660281 (-)	168	WP_011680762.1	hypothetical protein	-
NUU05_RS08690 (NUU05_08655)	-	1660357..1661520 (-)	1164	WP_011680761.1	MalY/PatB family protein	-
NUU05_RS08695 (NUU05_08660)	-	1661531..1662625 (-)	1095	WP_002946733.1	cystathionine gamma-synthase	-
NUU05_RS08700 (NUU05_08665)	-	1662929..1663522 (-)	594	Protein_1648	cation transporting ATPase C-terminal domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21577.62 Da
• Isoelectric Point: 4.4829

>NTDB_id=717649 NUU05_RS08670 WP_002949732.1 1658311..1658901(-) (clpP) [Streptococcus thermophilus strain TH-4]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPIEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEQILADNSGQ
PIEKVHVDAERDNWMSAQETLEYGFIDEIMTNNQLK

Nucleotide

• Length: 591 bp

>NTDB_id=717649 NUU05_RS08670 WP_002949732.1 1658311..1658901(-) (clpP) [Streptococcus thermophilus strain TH-4]
ATGATTCCGGTAGTTATTGAACAAACATCACGTGGTGAACGTTCTTATGACATTTACTCACGTTTGCTCAAGGATCGTAT
TATCATGTTAACAGGTCCTATAGAAGATAATATGGCAAACTCAATTATCGCTCAACTCTTGTTCTTGGATGCTCAAGACA
ATACAAAAGATATCTATCTGTATGTTAATACACCTGGTGGGTCAGTTTCAGCAGGCCTTGCCATTGTTGATACAATGAAC
TTCATCAAGTCTGATGTTCAAACCATCGTTATGGGGATGGCAGCATCAATGGGTACAATTATCGCTTCAAGCGGTACCAA
AGGTAAACGTTTCATGTTGCCAAATGCAGAATACATGATTCACCAACCAATGGGTGGTACTGGTGGTGGTACTCAACAAA
CAGATATGGCTATCGCTGCTGAACACTTGCTCAAGACTCGTAATAACTTGGAGCAAATCTTGGCTGATAATTCTGGTCAG
CCAATTGAAAAGGTTCATGTCGATGCTGAACGTGATAATTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTCATTGA
TGAAATCATGACCAACAACCAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: Q5M5U4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus thermophilus LMG 18311	100	100	1
clpP	Streptococcus thermophilus LMD-9	100	100	1
clpP	Streptococcus pneumoniae D39	92.821	99.49	0.923
clpP	Streptococcus pneumoniae R6	92.821	99.49	0.923
clpP	Streptococcus pneumoniae TIGR4	92.821	99.49	0.923
clpP	Streptococcus pneumoniae Rx1	92.821	99.49	0.923
clpP	Streptococcus pyogenes MGAS315	89.796	100	0.898
clpP	Streptococcus pyogenes JRS4	89.796	100	0.898
clpP	Streptococcus mutans UA159	87.755	100	0.878
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.245	100	0.872
clpP	Lactococcus lactis subsp. cremoris KW2	86.735	100	0.867
clpP	Bacillus subtilis subsp. subtilis str. 168	59.184	100	0.592
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.549	98.469	0.577