Detailed information NTG0717632

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: NUU05_RS05105
• Genome accession: NZ_CP102538
• Coordinates: 974935..975642 (+)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TH-4
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 969935..980642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUU05_RS05075 (NUU05_05055)	-	970218..970406 (+)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
NUU05_RS05080 (NUU05_05060)	endA	970468..971349 (+)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
NUU05_RS05085 (NUU05_05065)	-	971421..972071 (-)	651	WP_011226088.1	amino acid ABC transporter permease	-
NUU05_RS05090 (NUU05_05070)	-	972083..972781 (-)	699	WP_011681209.1	amino acid ABC transporter permease	-
NUU05_RS05095 (NUU05_05075)	-	972799..973632 (-)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
NUU05_RS05100 (NUU05_05080)	-	973644..974411 (-)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
NUU05_RS05105 (NUU05_05085)	vicR	974935..975642 (+)	708	WP_011681206.1	response regulator YycF	Regulator
NUU05_RS05110 (NUU05_05090)	vicK	975635..976975 (+)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
NUU05_RS05115 (NUU05_05095)	vicX	976981..977793 (+)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
NUU05_RS05120 (NUU05_05100)	-	977853..978214 (+)	362	Protein_950	YbaN family protein	-
NUU05_RS05125 (NUU05_05105)	-	978266..979480 (-)	1215	WP_011681202.1	aminoacyltransferase	-
NUU05_RS05130 (NUU05_05110)	yidA	979482..980291 (-)	810	WP_011681201.1	sugar-phosphatase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=717632 NUU05_RS05105 WP_011681206.1 974935..975642(+) (vicR) [Streptococcus thermophilus strain TH-4]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=717632 NUU05_RS05105 WP_011681206.1 974935..975642(+) (vicR) [Streptococcus thermophilus strain TH-4]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387