Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   NUU05_RS05110 Genome accession   NZ_CP102538
Coordinates   975635..976975 (+) Length   446 a.a.
NCBI ID   WP_011681205.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TH-4     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 970635..981975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NUU05_RS05085 (NUU05_05065) - 971421..972071 (-) 651 WP_011226088.1 amino acid ABC transporter permease -
  NUU05_RS05090 (NUU05_05070) - 972083..972781 (-) 699 WP_011681209.1 amino acid ABC transporter permease -
  NUU05_RS05095 (NUU05_05075) - 972799..973632 (-) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  NUU05_RS05100 (NUU05_05080) - 973644..974411 (-) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  NUU05_RS05105 (NUU05_05085) vicR 974935..975642 (+) 708 WP_011681206.1 response regulator YycF Regulator
  NUU05_RS05110 (NUU05_05090) vicK 975635..976975 (+) 1341 WP_011681205.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NUU05_RS05115 (NUU05_05095) vicX 976981..977793 (+) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  NUU05_RS05120 (NUU05_05100) - 977853..978214 (+) 362 Protein_950 YbaN family protein -
  NUU05_RS05125 (NUU05_05105) - 978266..979480 (-) 1215 WP_011681202.1 aminoacyltransferase -
  NUU05_RS05130 (NUU05_05110) yidA 979482..980291 (-) 810 WP_011681201.1 sugar-phosphatase -
  NUU05_RS05135 (NUU05_05115) - 980499..981377 (+) 879 Protein_953 GNAT family N-acetyltransferase -
  NUU05_RS05140 (NUU05_05120) - 981469..981855 (+) 387 WP_002953113.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50791.08 Da        Isoelectric Point: 5.3933

>NTDB_id=717633 NUU05_RS05110 WP_011681205.1 975635..976975(+) (vicK) [Streptococcus thermophilus strain TH-4]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=717633 NUU05_RS05110 WP_011681205.1 975635..976975(+) (vicK) [Streptococcus thermophilus strain TH-4]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

HAMP domain (HAMP)

(37-79)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

92.825

0.691
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641