Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   M0P28_RS00800 Genome accession   NZ_CP116958
Coordinates   119969..120262 (+) Length   97 a.a.
NCBI ID   WP_081048608.1    Uniprot ID   -
Organism   Streptococcus pasteurianus strain WUSP074     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 114969..125262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0P28_RS00775 (M0P28_00775) - 116966..117328 (+) 363 WP_058692629.1 DUF1033 family protein -
  M0P28_RS00780 (M0P28_00780) comGA 117399..118340 (+) 942 WP_003062917.1 competence type IV pilus ATPase ComGA Machinery gene
  M0P28_RS00785 (M0P28_00785) comGB 118264..119307 (+) 1044 WP_003062919.1 competence type IV pilus assembly protein ComGB Machinery gene
  M0P28_RS00790 (M0P28_00790) comGC 119307..119600 (+) 294 WP_117479472.1 competence type IV pilus major pilin ComGC Machinery gene
  M0P28_RS00795 (M0P28_00795) comGD 119584..120015 (+) 432 WP_058692630.1 competence type IV pilus minor pilin ComGD Machinery gene
  M0P28_RS00800 (M0P28_00800) comGE 119969..120262 (+) 294 WP_081048608.1 competence type IV pilus minor pilin ComGE Machinery gene
  M0P28_RS00805 (M0P28_00805) comGF 120216..120683 (+) 468 WP_058692632.1 competence type IV pilus minor pilin ComGF Machinery gene
  M0P28_RS00810 (M0P28_00810) comGG 120637..120987 (+) 351 WP_238374707.1 competence type IV pilus minor pilin ComGG Machinery gene
  M0P28_RS00815 (M0P28_00815) comGH 121042..122013 (+) 972 WP_117479470.1 class I SAM-dependent methyltransferase Machinery gene
  M0P28_RS00820 (M0P28_00820) - 122051..123250 (+) 1200 WP_058692635.1 acetate kinase -
  M0P28_RS00825 (M0P28_00825) - 123417..123617 (+) 201 WP_058692636.1 helix-turn-helix transcriptional regulator -
  M0P28_RS00830 (M0P28_00830) - 123627..123833 (+) 207 WP_058692637.1 hypothetical protein -
  M0P28_RS00835 (M0P28_00835) - 123824..124276 (+) 453 WP_117479468.1 ABC transporter permease -
  M0P28_RS00840 (M0P28_00840) - 124288..124923 (+) 636 WP_058692639.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11055.07 Da        Isoelectric Point: 8.4757

>NTDB_id=715224 M0P28_RS00800 WP_081048608.1 119969..120262(+) (comGE) [Streptococcus pasteurianus strain WUSP074]
MVNIKRQKLKAYILLESLIALGLLAMITSIVLGEIDKNRQFMQESLRQQEVLNVATMAVQTGQNHLKMNGIEVEIIKKDG
EVYVYEGKTEILHVKKD

Nucleotide


Download         Length: 294 bp        

>NTDB_id=715224 M0P28_RS00800 WP_081048608.1 119969..120262(+) (comGE) [Streptococcus pasteurianus strain WUSP074]
GTGGTAAATATAAAAAGACAGAAACTAAAAGCTTACATACTCCTTGAGAGCTTGATAGCACTAGGATTGTTAGCGATGAT
TACGAGTATTGTTTTAGGGGAAATTGATAAAAATAGGCAGTTTATGCAAGAAAGTTTACGGCAGCAGGAAGTTCTTAATG
TGGCAACAATGGCTGTGCAAACAGGGCAAAATCATTTGAAGATGAATGGTATTGAGGTTGAGATTATCAAAAAAGATGGA
GAGGTCTATGTTTATGAGGGGAAAACGGAAATATTACACGTTAAAAAAGACTAG

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

46.875

98.969

0.464
  comGE Streptococcus mutans UA159

46.875

98.969

0.464
  comGE/cglE Streptococcus mitis SK321

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae Rx1

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae D39

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae R6

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

41.489

96.907

0.402
  comGE/cglE Streptococcus mitis NCTC 12261

40.426

96.907

0.392