Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   M0P28_RS00815 Genome accession   NZ_CP116958
Coordinates   121042..122013 (+) Length   323 a.a.
NCBI ID   WP_117479470.1    Uniprot ID   -
Organism   Streptococcus pasteurianus strain WUSP074     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 116042..127013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0P28_RS00775 (M0P28_00775) - 116966..117328 (+) 363 WP_058692629.1 DUF1033 family protein -
  M0P28_RS00780 (M0P28_00780) comGA 117399..118340 (+) 942 WP_003062917.1 competence type IV pilus ATPase ComGA Machinery gene
  M0P28_RS00785 (M0P28_00785) comGB 118264..119307 (+) 1044 WP_003062919.1 competence type IV pilus assembly protein ComGB Machinery gene
  M0P28_RS00790 (M0P28_00790) comGC 119307..119600 (+) 294 WP_117479472.1 competence type IV pilus major pilin ComGC Machinery gene
  M0P28_RS00795 (M0P28_00795) comGD 119584..120015 (+) 432 WP_058692630.1 competence type IV pilus minor pilin ComGD Machinery gene
  M0P28_RS00800 (M0P28_00800) comGE 119969..120262 (+) 294 WP_081048608.1 competence type IV pilus minor pilin ComGE Machinery gene
  M0P28_RS00805 (M0P28_00805) comGF 120216..120683 (+) 468 WP_058692632.1 competence type IV pilus minor pilin ComGF Machinery gene
  M0P28_RS00810 (M0P28_00810) comGG 120637..120987 (+) 351 WP_238374707.1 competence type IV pilus minor pilin ComGG Machinery gene
  M0P28_RS00815 (M0P28_00815) comGH 121042..122013 (+) 972 WP_117479470.1 class I SAM-dependent methyltransferase Machinery gene
  M0P28_RS00820 (M0P28_00820) - 122051..123250 (+) 1200 WP_058692635.1 acetate kinase -
  M0P28_RS00825 (M0P28_00825) - 123417..123617 (+) 201 WP_058692636.1 helix-turn-helix transcriptional regulator -
  M0P28_RS00830 (M0P28_00830) - 123627..123833 (+) 207 WP_058692637.1 hypothetical protein -
  M0P28_RS00835 (M0P28_00835) - 123824..124276 (+) 453 WP_117479468.1 ABC transporter permease -
  M0P28_RS00840 (M0P28_00840) - 124288..124923 (+) 636 WP_058692639.1 CPBP family intramembrane glutamic endopeptidase -
  M0P28_RS00845 (M0P28_00845) proC 124967..125737 (-) 771 WP_058692640.1 pyrroline-5-carboxylate reductase -
  M0P28_RS00850 (M0P28_00850) pepA 125798..126865 (-) 1068 WP_058692641.1 glutamyl aminopeptidase -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36622.67 Da        Isoelectric Point: 4.4130

>NTDB_id=715227 M0P28_RS00815 WP_117479470.1 121042..122013(+) (comGH) [Streptococcus pasteurianus strain WUSP074]
MNFEKIETAYELILENIQLIENELKTHIYDALIEQNSFYLGAEGASEEVAANNEKLRQLALTKEEWRRAFQFIFIKAGQT
EQLQANHQFTPDAIGFILLFLIENLTDSDKIDLLEIGSGTGNLAQTFLNNSSKELNYLGIEVDDLLIDLSASIAEVMDSD
ARFIQEDAVRPQILQESDVIISDLPVGFYPNDDIAKRYKVASSDEHTYAHHLLMEQSLKYLKKDGIAVFLAPVSLLTSKQ
SDLLKQWLKDYADIIAVITLPESIFGNVANAKSIFVLKKQAAQTPETFVYPLSDLQSRETLTDFIGKFQKWKVDNMNFKK
NVI

Nucleotide


Download         Length: 972 bp        

>NTDB_id=715227 M0P28_RS00815 WP_117479470.1 121042..122013(+) (comGH) [Streptococcus pasteurianus strain WUSP074]
ATGAATTTTGAAAAAATTGAAACAGCCTATGAGCTGATTTTAGAAAATATCCAATTAATTGAAAATGAGTTAAAAACTCA
TATTTATGATGCGCTTATTGAACAGAACTCTTTTTACTTGGGTGCTGAAGGTGCCAGTGAAGAAGTTGCTGCCAACAATG
AGAAACTGCGTCAGCTTGCATTGACCAAAGAAGAGTGGCGTCGAGCTTTCCAATTTATCTTTATCAAAGCTGGTCAAACA
GAGCAACTGCAAGCCAATCATCAATTTACACCAGATGCTATTGGTTTTATTTTGCTGTTCTTGATTGAAAATCTGACAGA
TTCAGATAAAATTGACCTTTTAGAAATTGGTAGTGGGACAGGGAACCTTGCTCAAACATTCTTAAATAATTCGTCTAAAG
AATTAAATTATCTTGGTATTGAAGTTGACGATTTGTTGATTGATTTATCAGCAAGTATTGCAGAAGTGATGGATTCTGAT
GCTCGGTTTATTCAAGAAGACGCTGTGCGTCCACAAATTCTACAAGAAAGTGATGTGATTATTAGTGATTTGCCAGTGGG
TTTCTATCCTAATGATGACATTGCAAAACGTTATAAAGTGGCAAGTTCTGATGAGCATACCTATGCCCACCATTTGTTAA
TGGAACAATCGTTAAAATATCTCAAAAAAGATGGTATTGCAGTCTTTTTGGCGCCCGTTAGTCTTTTGACAAGCAAACAG
AGTGATTTATTGAAACAATGGTTGAAAGATTACGCGGATATTATCGCCGTGATTACTTTGCCAGAATCTATTTTTGGCAA
TGTAGCGAATGCGAAATCAATTTTTGTTTTGAAAAAACAGGCTGCGCAGACGCCAGAAACCTTTGTTTATCCACTTTCTG
ACTTACAAAGTCGTGAAACTCTGACCGATTTCATTGGAAAATTTCAAAAATGGAAAGTTGATAATATGAATTTTAAAAAA
AATGTGATATAA

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(70-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA140

68.987

97.833

0.675
  comGH Streptococcus mutans UA159

68.671

97.833

0.672