Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   NQZ91_RS00645 Genome accession   NZ_CP102145
Coordinates   128914..129618 (+) Length   234 a.a.
NCBI ID   WP_105122701.1    Uniprot ID   -
Organism   Streptococcus suis strain DNS20     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 123914..134618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ91_RS00620 (NQZ91_00620) - 124213..125259 (+) 1047 WP_257104599.1 zinc-binding dehydrogenase -
  NQZ91_RS00625 (NQZ91_00625) - 125433..126092 (-) 660 WP_105110789.1 amino acid ABC transporter permease -
  NQZ91_RS00630 (NQZ91_00630) - 126104..126802 (-) 699 WP_125266253.1 amino acid ABC transporter permease -
  NQZ91_RS00635 (NQZ91_00635) - 127112..127951 (-) 840 WP_105110791.1 transporter substrate-binding domain-containing protein -
  NQZ91_RS00640 (NQZ91_00640) - 127961..128722 (-) 762 WP_257104598.1 amino acid ABC transporter ATP-binding protein -
  NQZ91_RS00645 (NQZ91_00645) micA 128914..129618 (+) 705 WP_105122701.1 response regulator YycF Regulator
  NQZ91_RS00650 (NQZ91_00650) micB 129611..130960 (+) 1350 WP_105122702.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NQZ91_RS00655 (NQZ91_00655) vicX 130966..131769 (+) 804 WP_257117614.1 MBL fold metallo-hydrolase Regulator
  NQZ91_RS00660 (NQZ91_00660) pbp2b 132095..134182 (+) 2088 WP_398599413.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26798.89 Da        Isoelectric Point: 4.8849

>NTDB_id=714923 NQZ91_RS00645 WP_105122701.1 128914..129618(+) (micA) [Streptococcus suis strain DNS20]
MKKILVVDDERPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARNIRKTSNVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELTETQSIPVVAGKAELVIGDLVILPDAFVAKKHGKELELT
HREFELLYHLAQHIGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDIPSRPEYILTRRGVGYFIKAND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=714923 NQZ91_RS00645 WP_105122701.1 128914..129618(+) (micA) [Streptococcus suis strain DNS20]
ATGAAAAAAATTCTAGTTGTAGATGATGAGAGACCTATCTCGGATATTATTAAATTTAACATGACCCGTGAGGGCTATGA
GGTCGTGACAGCTTTTGATGGTCGCGAGGCCTTAGAAGTATTTGAAGCGGAGTTTCCGGACATTGTCATTCTGGATTTGA
TGTTGCCAGAGTTGGATGGTTTGGAAGTGGCCCGTAACATTCGCAAGACCAGCAATGTGCCCATTATTATGTTGTCTGCC
AAGGATAGCGAATTTGACAAGGTTATTGGCTTGGAAATTGGAGCGGACGATTATGTGACCAAGCCTTTCTCTAACCGTGA
ATTGCAGGCCCGCGTCAAGGCTCTGCTTCGCCGGAGCGAGTTGACAGAGACCCAGTCCATTCCTGTTGTGGCTGGCAAGG
CGGAATTGGTCATCGGAGACCTGGTGATTTTGCCCGATGCCTTTGTTGCCAAAAAACATGGTAAGGAATTGGAATTGACC
CACCGGGAGTTCGAGCTGCTCTATCATCTGGCCCAACACATTGGTCAAGTCATGACCCGCGAGCACTTGCTGGAAACAGT
TTGGGGCTATGATTACTTTGGTGATGTCCGGACGGTCGACGTGACGGTTCGTCGTTTGCGTGAGAAAATCGAAGACATTC
CAAGCCGCCCTGAATACATCTTGACCCGCCGTGGCGTCGGGTACTTTATAAAAGCCAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

80.672

100

0.821
  vicR Streptococcus mutans UA159

78.723

100

0.791
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.913

98.291

0.432
  covR Streptococcus salivarius strain HSISS4

42.857

98.718

0.423
  scnR Streptococcus mutans UA159

36.17

100

0.363