Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   NQZ91_RS00650 Genome accession   NZ_CP102145
Coordinates   129611..130960 (+) Length   449 a.a.
NCBI ID   WP_105122702.1    Uniprot ID   -
Organism   Streptococcus suis strain DNS20     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 124611..135960
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ91_RS00625 (NQZ91_00625) - 125433..126092 (-) 660 WP_105110789.1 amino acid ABC transporter permease -
  NQZ91_RS00630 (NQZ91_00630) - 126104..126802 (-) 699 WP_125266253.1 amino acid ABC transporter permease -
  NQZ91_RS00635 (NQZ91_00635) - 127112..127951 (-) 840 WP_105110791.1 transporter substrate-binding domain-containing protein -
  NQZ91_RS00640 (NQZ91_00640) - 127961..128722 (-) 762 WP_257104598.1 amino acid ABC transporter ATP-binding protein -
  NQZ91_RS00645 (NQZ91_00645) micA 128914..129618 (+) 705 WP_105122701.1 response regulator YycF Regulator
  NQZ91_RS00650 (NQZ91_00650) micB 129611..130960 (+) 1350 WP_105122702.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NQZ91_RS00655 (NQZ91_00655) vicX 130966..131769 (+) 804 WP_257117614.1 MBL fold metallo-hydrolase Regulator
  NQZ91_RS00660 (NQZ91_00660) pbp2b 132095..134182 (+) 2088 WP_398599413.1 penicillin-binding protein PBP2B -
  NQZ91_RS00665 (NQZ91_00665) recR 134191..134787 (+) 597 WP_105128095.1 recombination mediator RecR -
  NQZ91_RS00670 (NQZ91_00670) - 134869..135915 (+) 1047 WP_257104594.1 D-alanine--D-alanine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51220.33 Da        Isoelectric Point: 4.4768

>NTDB_id=714924 NQZ91_RS00650 WP_105122702.1 129611..130960(+) (micB) [Streptococcus suis strain DNS20]
MINQLRYLITTSEFWFIVISIGFVIAITVLLIENYRDNKQIKQLNERVKSLMEGDYADVLDLRGSPEITDMTNSLNDLSE
MIRLTHDNLEQEKTRLSSILSYMSDGVVATDRMGRIIMINDMAQKQLGLSVQEATQSDILDVLELQEEYSFRELLAQTPE
IVLEHTNENQEFLTLRANFATIRSESGLISGLVIVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIT
ETVAPSFVKVSLDETNRMMRMITDLLSLSRFDNQVGELNLELINFTAFVTFILNRFDQMKNSDSEKIYSIVRDYQISPIW
IEIDTDKMTQVLDNILNNAIKYSPDGGKITFSMKTTDSQLIVSISDQGLGIPKADLPKIFDRFYRVDKARSRSQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKEIAMDEWDDTLEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=714924 NQZ91_RS00650 WP_105122702.1 129611..130960(+) (micB) [Streptococcus suis strain DNS20]
ATGATTAATCAACTGCGTTACCTGATAACGACCTCGGAATTCTGGTTTATTGTCATCAGTATTGGCTTTGTGATTGCCAT
TACAGTTCTCTTGATTGAGAATTACCGGGACAATAAGCAGATTAAACAATTAAATGAACGTGTTAAGTCGCTCATGGAAG
GGGATTATGCGGATGTTCTGGATTTAAGAGGTAGTCCGGAAATTACGGATATGACCAACTCCTTGAACGATTTGTCTGAA
ATGATTCGTCTGACGCATGATAATTTGGAACAGGAAAAAACACGCCTCAGTTCCATTTTGTCTTATATGAGTGATGGTGT
CGTGGCAACCGATCGAATGGGGCGCATCATTATGATTAACGACATGGCCCAGAAACAATTAGGTTTGAGCGTACAGGAGG
CGACGCAATCAGATATCTTGGATGTTTTGGAACTCCAGGAGGAATACAGCTTTCGTGAATTGCTGGCTCAGACACCGGAA
ATTGTGCTTGAGCACACCAATGAAAACCAGGAATTTCTGACACTTCGGGCAAATTTTGCGACCATTCGGAGCGAAAGTGG
CTTGATTTCTGGTCTGGTTATTGTCCTGCATGATATGACTGAGCAGGCCAAGGAAGAGCGGGAGCGGCGGCTCTTTGTAT
CTAATGTTAGCCACGAGTTGCGGACACCTCTAACATCTGTCAAGTCTTATCTAGAAGCCTTGGACGAGGGTGCTATTACA
GAAACGGTGGCTCCAAGCTTTGTCAAGGTTTCTCTAGATGAGACCAACCGCATGATGAGGATGATTACGGATCTCCTGAG
CCTGTCACGTTTTGACAATCAAGTCGGTGAGTTGAATCTAGAATTGATTAACTTCACGGCCTTTGTCACCTTTATTCTCA
ACCGTTTTGATCAGATGAAGAATTCAGATTCTGAGAAGATTTATTCGATTGTGCGAGACTATCAGATTAGTCCGATTTGG
ATAGAAATTGATACGGACAAGATGACCCAGGTTTTGGACAATATCCTGAATAATGCAATCAAGTATTCGCCGGATGGGGG
CAAAATCACTTTCAGTATGAAGACCACGGACAGTCAGCTGATTGTCTCCATCTCTGACCAAGGGCTGGGAATTCCCAAGG
CTGATTTGCCTAAGATTTTTGACCGATTTTACCGGGTGGACAAGGCACGTTCGCGGTCCCAAGGGGGGACAGGTCTGGGC
TTGGCCATTGCCAAGGAAATTGTGAAACAGCATAAAGGTTTTATTTGGGCCAAGTCAGAATATGGACATGGTTCGACCTT
TACTATTGTCTTGCCATACAGTAAGGAAATCGCTATGGATGAGTGGGATGACACTCTTGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.266

97.105

0.673
  vicK Streptococcus mutans UA159

69.231

89.755

0.621