Detailed information NTG0714295

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: NQZ84_RS04260
• Genome accession: NZ_CP102094
• Coordinates: 857274..857945 (+)
• Length: 223 a.a.
• NCBI ID: WP_024385291.1
• Uniprot ID: A0A116K182
• Organism: Streptococcus suis strain 12RC1
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 852274..862945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ84_RS04230 (NQZ84_04230)	pstC	852456..853373 (+)	918	WP_002937619.1	phosphate ABC transporter permease subunit PstC	-
NQZ84_RS04235 (NQZ84_04235)	pstA	853363..854250 (+)	888	WP_014635996.1	phosphate ABC transporter permease PstA	-
NQZ84_RS04240 (NQZ84_04240)	pstB	854275..855078 (+)	804	WP_024399032.1	phosphate ABC transporter ATP-binding protein PstB	-
NQZ84_RS04245 (NQZ84_04245)	pstB	855090..855848 (+)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
NQZ84_RS04250 (NQZ84_04250)	phoU	855877..856533 (+)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
NQZ84_RS04255 (NQZ84_04255)	-	856699..857079 (+)	381	WP_014637851.1	hypothetical protein	-
NQZ84_RS04260 (NQZ84_04260)	ciaR	857274..857945 (+)	672	WP_024385291.1	response regulator transcription factor	Regulator
NQZ84_RS04265 (NQZ84_04265)	ciaH	857938..859317 (+)	1380	WP_257048524.1	sensor histidine kinase	Regulator
NQZ84_RS04270 (NQZ84_04270)	-	859418..860647 (+)	1230	WP_044753111.1	transglutaminase domain-containing protein	-
NQZ84_RS04275 (NQZ84_04275)	rpsT	860867..861115 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
NQZ84_RS04280 (NQZ84_04280)	coaA	861174..862094 (-)	921	WP_002935283.1	type I pantothenate kinase	-
NQZ84_RS04285 (NQZ84_04285)	-	862203..862793 (+)	591	WP_024376492.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25231.80 Da
• Isoelectric Point: 4.2183

>NTDB_id=714295 NQZ84_RS04260 WP_024385291.1 857274..857945(+) (ciaR) [Streptococcus suis strain 12RC1]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNSTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=714295 NQZ84_RS04260 WP_024385291.1 857274..857945(+) (ciaR) [Streptococcus suis strain 12RC1]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTGGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGAGAAGAGGGTGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTTTTGAAAGAGTTACGTGAAAAAGGTGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACTTATGGGGACGTGACCG
TTGACTTATCGACAAACTCTACAACTGTAAATGGTGAAGAAGTTGAATTGCTAGGAAAAGAATTCGATCTACTAGTCTAC
TTCTTGCAAAATCAAAATGTTATCTTACCAAAAACTCAAATTTTTGACCGTATTTGGGGATTTGACAGTGACACTACTAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTCGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.789	100	0.888
ciaR	Streptococcus pneumoniae D39	88.789	100	0.888
ciaR	Streptococcus pneumoniae R6	88.789	100	0.888
ciaR	Streptococcus pneumoniae TIGR4	88.789	100	0.888
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	36.283	100	0.368