Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NQZ84_RS04265 Genome accession   NZ_CP102094
Coordinates   857938..859317 (+) Length   459 a.a.
NCBI ID   WP_257048524.1    Uniprot ID   -
Organism   Streptococcus suis strain 12RC1     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 852938..864317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ84_RS04235 (NQZ84_04235) pstA 853363..854250 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  NQZ84_RS04240 (NQZ84_04240) pstB 854275..855078 (+) 804 WP_024399032.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ84_RS04245 (NQZ84_04245) pstB 855090..855848 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ84_RS04250 (NQZ84_04250) phoU 855877..856533 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  NQZ84_RS04255 (NQZ84_04255) - 856699..857079 (+) 381 WP_014637851.1 hypothetical protein -
  NQZ84_RS04260 (NQZ84_04260) ciaR 857274..857945 (+) 672 WP_024385291.1 response regulator transcription factor Regulator
  NQZ84_RS04265 (NQZ84_04265) ciaH 857938..859317 (+) 1380 WP_257048524.1 sensor histidine kinase Regulator
  NQZ84_RS04270 (NQZ84_04270) - 859418..860647 (+) 1230 WP_044753111.1 transglutaminase domain-containing protein -
  NQZ84_RS04275 (NQZ84_04275) rpsT 860867..861115 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  NQZ84_RS04280 (NQZ84_04280) coaA 861174..862094 (-) 921 WP_002935283.1 type I pantothenate kinase -
  NQZ84_RS04285 (NQZ84_04285) - 862203..862793 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  NQZ84_RS04290 (NQZ84_04290) - 862790..864067 (+) 1278 WP_044680727.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51861.42 Da        Isoelectric Point: 6.5295

>NTDB_id=714296 NQZ84_RS04265 WP_257048524.1 857938..859317(+) (ciaH) [Streptococcus suis strain 12RC1]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKEQKNTRDGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLPLDKEKLGEIKETTVESSFGM
SEDYRYVTTELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVTDNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=714296 NQZ84_RS04265 WP_257048524.1 857938..859317(+) (ciaH) [Streptococcus suis strain 12RC1]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGAACAAAAAAATACTAGGGATGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGACTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACTTATGAATCGACAGTTGCTATTGTTATGGTTTCAG
CGTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGTATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTATTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACAAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCGAATTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTTATTAAACAGTTACTTACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACTGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTACCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae D39

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae R6

49.563

99.782

0.495
  ciaH Streptococcus pneumoniae TIGR4

49.563

99.782

0.495
  ciaH Streptococcus mutans UA159

50.336

97.386

0.49