Detailed information    

insolico Bioinformatically predicted

Overview


Name   clpP   Type   Regulator
Locus tag   NPS16_RS07705 Genome accession   NZ_CP101986
Coordinates   1657597..1658211 (-) Length   204 a.a.
NCBI ID   WP_255262943.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14     
Function   degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology)   
Competence regulation

Genomic Context


Location: 1652597..1663211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS16_RS07675 (NPS16_07675) - 1652822..1653586 (-) 765 WP_002301888.1 ABC transporter ATP-binding protein -
  NPS16_RS07680 (NPS16_07680) - 1653586..1654542 (-) 957 WP_002262677.1 branched-chain amino acid ABC transporter permease -
  NPS16_RS07685 (NPS16_07685) - 1654546..1655415 (-) 870 WP_002262676.1 branched-chain amino acid ABC transporter permease -
  NPS16_RS07690 (NPS16_07690) - 1655499..1656671 (-) 1173 WP_002262675.1 ABC transporter substrate-binding protein -
  NPS16_RS07695 (NPS16_07695) - 1656779..1657027 (-) 249 WP_002262674.1 YlbG family protein -
  NPS16_RS07700 (NPS16_07700) - 1657034..1657474 (-) 441 WP_002264032.1 YlbF family regulator -
  NPS16_RS07705 (NPS16_07705) clpP 1657597..1658211 (-) 615 WP_255262943.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  NPS16_RS07710 (NPS16_07710) upp 1658520..1659149 (-) 630 WP_258968860.1 uracil phosphoribosyltransferase -
  NPS16_RS07715 (NPS16_07715) - 1659462..1660625 (-) 1164 WP_002266835.1 MalY/PatB family protein -
  NPS16_RS07720 (NPS16_07720) - 1660640..1661734 (-) 1095 WP_002274783.1 cystathionine gamma-synthase -

Sequence


Protein


Download         Length: 204 a.a.        Molecular weight: 22665.10 Da        Isoelectric Point: 5.3673

>NTDB_id=713662 NPS16_RS07705 WP_255262943.1 1657597..1658211(-) (clpP) [Streptococcus mutans strain COCC33-14]
MELKEKYSMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINSPGGSVSAG
LAIVDTMNFIKSDVQTIVMGIAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGGGTQQSDMAIAAEQLLKTRKKLEK
ILSDNSGKTVKQIHKDAERDYWMDAKETLKYGFIDEIMENNELK

Nucleotide


Download         Length: 615 bp        

>NTDB_id=713662 NPS16_RS07705 WP_255262943.1 1657597..1658211(-) (clpP) [Streptococcus mutans strain COCC33-14]
ATTGAATTAAAGGAGAAATACAGTATGATTCCTGTAGTTATTGAACAAACGAGCCGTGGTGAACGCTCTTATGATATTTA
TTCACGTCTATTAAAAGATCGTATTATTATGTTGACTGGTCCTGTTGAAGACAATATGGCAAATTCCATTATTGCTCAGT
TACTGTTTCTTGATGCACAAGATAATACCAAAGACATTTATCTTTATATTAATTCACCGGGTGGTTCTGTTTCAGCTGGT
CTTGCTATTGTTGATACGATGAACTTTATTAAGTCTGATGTTCAAACGATTGTTATGGGTATTGCTGCTTCCATGGGAAC
AATCATCGCTTCTAGCGGTGCCAAAGGAAAACGTTTTATGTTACCAAATGCAGAATATCTTATCCATCAGCCAATGGGCG
GTACAGGCGGTGGCACACAGCAGTCTGATATGGCTATTGCTGCCGAACAATTGCTTAAAACACGCAAAAAATTAGAAAAG
ATTCTATCGGATAATTCTGGAAAAACAGTAAAACAAATTCATAAGGATGCTGAACGTGATTATTGGATGGATGCTAAGGA
AACATTAAAGTATGGCTTCATCGATGAAATCATGGAAAATAATGAATTAAAATAA

Domains


Predicted by InterproScan.

(19-200)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus mutans UA159

99.51

100

0.995

  clpP Streptococcus pyogenes JRS4

90.306

96.078

0.868

  clpP Streptococcus pyogenes MGAS315

90.306

96.078

0.868

  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.755

96.078

0.843

  clpP Streptococcus thermophilus LMD-9

87.245

96.078

0.838

  clpP Lactococcus lactis subsp. cremoris KW2

87.245

96.078

0.838

  clpP Streptococcus thermophilus LMG 18311

87.245

96.078

0.838

  clpP Streptococcus pneumoniae Rx1

86.154

95.588

0.824

  clpP Streptococcus pneumoniae D39

86.154

95.588

0.824

  clpP Streptococcus pneumoniae R6

86.154

95.588

0.824

  clpP Streptococcus pneumoniae TIGR4

86.154

95.588

0.824

  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.513

94.608

0.544

  clpP Bacillus subtilis subsp. subtilis str. 168

55.838

96.569

0.539