Detailed information NTG0713575

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NPS17_RS04665
• Genome accession: NZ_CP101985
• Coordinates: 1034814..1035656 (+)
• Length: 280 a.a.
• NCBI ID: WP_002262865.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain COCC33-14R
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1029814..1040656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NPS17_RS04640 (NPS17_04640)	-	1030497..1031459 (+)	963	WP_168749588.1	ABC transporter permease	-
NPS17_RS04645 (NPS17_04645)	-	1031456..1032427 (+)	972	WP_002275899.1	iron chelate uptake ABC transporter family permease subunit	-
NPS17_RS04650 (NPS17_04650)	-	1032424..1033230 (+)	807	WP_002270389.1	ABC transporter ATP-binding protein	-
NPS17_RS04655 (NPS17_04655)	-	1033278..1034294 (+)	1017	WP_179957224.1	siderophore ABC transporter substrate-binding protein	-
NPS17_RS04660 (NPS17_04660)	-	1034366..1034647 (+)	282	WP_002262863.1	hypothetical protein	-
NPS17_RS04665 (NPS17_04665)	dprA	1034814..1035656 (+)	843	WP_002262865.1	DNA-processing protein DprA	Machinery gene
NPS17_RS04670 (NPS17_04670)	topA	1035751..1037868 (+)	2118	WP_168749590.1	type I DNA topoisomerase	-
NPS17_RS04675 (NPS17_04675)	trmFO	1038234..1039568 (+)	1335	WP_002309566.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31332.27 Da
• Isoelectric Point: 9.1954

>NTDB_id=713575 NPS17_RS04665 WP_002262865.1 1034814..1035656(+) (dprA) [Streptococcus mutans strain COCC33-14R]
MDNFQLFKLKKAGLTNLNILNIIDYEERTQKSLSLRDMAVVSKNKKPLIFMEHYKNLDSKALRKEFNRFPSLSILDKEYP
LELKNIYNPPVLLFYQGDLDLLARPKLAVVGSRNASQMGVAAVKKIIQDLSKQFVIISGLARGIDTAAHLASLKSGGATI
AVIGTGLDVHYPKENRRLQDYIAKNHLLLSEYEAQSQPLKYHFPERNRIIAGLSQGVMVAEAKIRSGSLITCERAMEEGR
DVFVVPGNILDGQSEGCHHLIQEGAKCITSGFDILNEFNF

Nucleotide

• Length: 843 bp

>NTDB_id=713575 NPS17_RS04665 WP_002262865.1 1034814..1035656(+) (dprA) [Streptococcus mutans strain COCC33-14R]
ATGGATAATTTTCAACTATTTAAACTTAAAAAAGCTGGTCTAACAAATCTGAATATCTTAAATATTATTGATTATGAAGA
GAGGACACAAAAATCCTTGTCTCTTCGTGATATGGCTGTTGTTTCCAAAAATAAAAAGCCTTTAATTTTTATGGAACATT
ACAAGAATCTTGATAGCAAAGCATTACGCAAAGAATTTAATCGTTTTCCTTCTTTATCCATTTTGGACAAAGAATATCCC
TTGGAACTTAAAAATATTTATAATCCGCCTGTTCTTCTATTTTATCAGGGAGACTTAGACTTGCTAGCTCGGCCTAAATT
AGCAGTAGTTGGTTCTCGCAACGCCAGTCAAATGGGAGTAGCTGCTGTTAAAAAGATCATACAAGACTTAAGTAAGCAAT
TTGTTATTATTAGCGGTTTAGCGCGTGGTATTGATACTGCAGCACATTTAGCAAGTCTTAAAAGCGGTGGAGCAACAATT
GCGGTCATCGGTACTGGACTAGATGTTCATTATCCTAAAGAAAATCGAAGACTGCAGGATTATATTGCAAAGAATCATTT
GCTCTTATCAGAATATGAAGCACAGAGTCAACCTCTTAAGTATCATTTTCCTGAGCGGAACCGCATTATTGCTGGGTTAT
CTCAAGGTGTTATGGTAGCAGAAGCAAAAATTCGTTCGGGTAGTCTGATTACTTGTGAACGTGCTATGGAAGAAGGACGC
GATGTTTTTGTTGTACCAGGAAATATTTTAGACGGCCAGTCAGAAGGATGCCATCACCTGATTCAAGAAGGAGCAAAATG
CATTACATCAGGCTTTGATATTTTAAATGAGTTTAACTTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	100	100	1
dprA/cilB/dalA	Streptococcus mitis SK321	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.857	100	0.629
dprA	Lactococcus lactis subsp. cremoris KW2	58.273	99.286	0.579
dprA	Legionella pneumophila strain ERS1305867	44.77	85.357	0.382
dprA	Staphylococcus aureus N315	38.258	94.286	0.361