Detailed information NTG0713500

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NPS18_RS04680
• Genome accession: NZ_CP101984
• Coordinates: 945717..946559 (+)
• Length: 280 a.a.
• NCBI ID: WP_002262865.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain UA-159
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 940717..951559

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NPS18_RS04655 (NPS18_04655)	-	941400..942362 (+)	963	WP_002262859.1	ABC transporter permease	-
NPS18_RS04660 (NPS18_04660)	-	942359..943330 (+)	972	WP_002262860.1	iron chelate uptake ABC transporter family permease subunit	-
NPS18_RS04665 (NPS18_04665)	-	943327..944133 (+)	807	WP_002262861.1	ABC transporter ATP-binding protein	-
NPS18_RS04670 (NPS18_04670)	-	944181..945197 (+)	1017	WP_002262862.1	siderophore ABC transporter substrate-binding protein	-
NPS18_RS04675 (NPS18_04675)	-	945269..945550 (+)	282	WP_002262863.1	hypothetical protein	-
NPS18_RS04680 (NPS18_04680)	dprA	945717..946559 (+)	843	WP_002262865.1	DNA-processing protein DprA	Machinery gene
NPS18_RS04685 (NPS18_04685)	topA	946654..948771 (+)	2118	WP_002262866.1	type I DNA topoisomerase	-
NPS18_RS04690 (NPS18_04690)	trmFO	949137..950471 (+)	1335	WP_002262867.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31332.27 Da
• Isoelectric Point: 9.1954

>NTDB_id=713500 NPS18_RS04680 WP_002262865.1 945717..946559(+) (dprA) [Streptococcus mutans strain UA-159]
MDNFQLFKLKKAGLTNLNILNIIDYEERTQKSLSLRDMAVVSKNKKPLIFMEHYKNLDSKALRKEFNRFPSLSILDKEYP
LELKNIYNPPVLLFYQGDLDLLARPKLAVVGSRNASQMGVAAVKKIIQDLSKQFVIISGLARGIDTAAHLASLKSGGATI
AVIGTGLDVHYPKENRRLQDYIAKNHLLLSEYEAQSQPLKYHFPERNRIIAGLSQGVMVAEAKIRSGSLITCERAMEEGR
DVFVVPGNILDGQSEGCHHLIQEGAKCITSGFDILNEFNF

Nucleotide

• Length: 843 bp

>NTDB_id=713500 NPS18_RS04680 WP_002262865.1 945717..946559(+) (dprA) [Streptococcus mutans strain UA-159]
ATGGATAATTTTCAACTATTTAAACTTAAAAAAGCTGGTCTAACAAATCTGAATATCTTAAATATTATTGATTATGAAGA
GAGGACACAAAAATCCTTGTCTCTTCGTGATATGGCTGTTGTTTCCAAAAATAAAAAGCCTTTAATTTTTATGGAACATT
ACAAAAATCTTGATAGCAAAGCATTACGCAAAGAATTTAATCGTTTTCCTTCTTTATCCATTTTGGACAAAGAATATCCC
TTGGAACTTAAAAATATTTATAATCCGCCTGTTCTTCTATTTTATCAGGGAGACTTAGACTTGCTAGCTCGGCCTAAATT
AGCAGTAGTTGGTTCTCGCAACGCCAGTCAAATGGGAGTAGCTGCTGTTAAAAAGATCATACAAGACTTAAGTAAGCAAT
TTGTTATTATTAGCGGTTTAGCGCGTGGTATTGATACTGCAGCACATTTAGCAAGTCTTAAAAGCGGTGGAGCAACAATT
GCGGTCATCGGTACTGGACTAGATGTTCATTATCCTAAAGAAAATCGAAGACTGCAGGATTATATTGCAAAGAATCATTT
GCTCTTATCAGAATATGAAGCACAGAGTCAACCTCTTAAGTATCATTTTCCTGAGCGGAACCGCATTATTGCTGGGTTAT
CTCAAGGTGTTATGGTAGCAGAAGCAAAAATTCGTTCGGGTAGTCTGATTACTTGTGAACGTGCTATGGAAGAAGGACGC
GATGTTTTTGTTGTACCAGGAAATATTTTAGACGGCCAGTCAGAAGGATGCCATCACCTGATTCAAGAAGGAGCAAAATG
CATTACATCAGGCTTTGATATTTTAAATGAGTTTAACTTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	100	100	1
dprA/cilB/dalA	Streptococcus mitis SK321	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.857	100	0.629
dprA	Lactococcus lactis subsp. cremoris KW2	58.273	99.286	0.579
dprA	Legionella pneumophila strain ERS1305867	44.77	85.357	0.382
dprA	Staphylococcus aureus N315	38.258	94.286	0.361