Detailed information NTG0712606

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: NPS25_RS17025
• Genome accession: NZ_CP101904
• Coordinates: 3450226..3450822 (+)
• Length: 198 a.a.
• NCBI ID: WP_003151513.1
• Uniprot ID: I2CAH7
• Organism: Bacillus velezensis strain Ba-0321
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3445226..3455822

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NPS25_RS17000 (NPS25_17000)	-	3445234..3445545 (+)	312	WP_007407407.1	hypothetical protein	-
NPS25_RS17010 (NPS25_17010)	-	3445897..3447366 (-)	1470	WP_156240492.1	glycoside hydrolase family 32 protein	-
NPS25_RS17015 (NPS25_17015)	-	3447381..3448613 (-)	1233	WP_061890842.1	MFS transporter	-
NPS25_RS17020 (NPS25_17020)	-	3449004..3449978 (+)	975	WP_015418285.1	LacI family DNA-binding transcriptional regulator	-
NPS25_RS17025 (NPS25_17025)	clpP	3450226..3450822 (+)	597	WP_003151513.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
NPS25_RS17030 (NPS25_17030)	-	3450866..3451726 (-)	861	WP_003151510.1	LysR family transcriptional regulator	-
NPS25_RS17035 (NPS25_17035)	-	3451900..3453030 (+)	1131	WP_015418286.1	2-methylaconitate cis-trans isomerase PrpF family protein	-
NPS25_RS17040 (NPS25_17040)	-	3453074..3454450 (+)	1377	WP_015418287.1	MFS transporter	-
NPS25_RS17045 (NPS25_17045)	-	3454694..3455269 (-)	576	WP_015387658.1	TIGR00730 family Rossman fold protein	-
NPS25_RS17050 (NPS25_17050)	-	3455385..3455705 (+)	321	WP_003151506.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21831.06 Da
• Isoelectric Point: 4.6982

>NTDB_id=712606 NPS25_RS17025 WP_003151513.1 3450226..3450822(+) (clpP) [Bacillus velezensis strain Ba-0321]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSADEALEYGLIDKVLTRNTEDQK

Nucleotide

• Length: 597 bp

>NTDB_id=712606 NPS25_RS17025 WP_003151513.1 3450226..3450822(+) (clpP) [Bacillus velezensis strain Ba-0321]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCTTATGACATTTACTCCCGTCTTTTGAAGGA
CCGTATTATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCCTTGAAGCGG
AAGACCCTGAAAAAGATATTTCCATTTACATTAACAGCCCTGGCGGATCAATCACTGCCGGCATGGCAATCTATGATACA
ATGCAGTTCATTAAACCGAAAGTATCCACGATCTGCATCGGTATGGCCGCTTCTATGGGAGCATTTTTACTTGCAGCCGG
AGAAAAAGGCAAACGTTACGCGCTTCCTAACAGTGAAGTTATGATTCACCAGCCGCTTGGCGGAGCGCAAGGACAGGCGA
CAGAAATTGAAATCGCGGCAAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTGCTTGCTGAACGTACCGGCCAG
CCGCTTGAAGTCATTGAGCGCGATACAGACCGCGACAACTTCAAATCAGCTGATGAAGCCTTAGAATACGGCTTAATCGA
TAAAGTGCTGACACGCAATACAGAAGACCAGAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: I2CAH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	95.96	100	0.96
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.586	96.465	0.662
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Streptococcus pneumoniae D39	57.216	97.98	0.561
clpP	Streptococcus pneumoniae Rx1	57.216	97.98	0.561
clpP	Streptococcus pneumoniae R6	57.216	97.98	0.561
clpP	Streptococcus pneumoniae TIGR4	57.216	97.98	0.561
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	97.98	0.556
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.639	97.98	0.535
clpP	Streptococcus mutans UA159	54.639	97.98	0.535