Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   K6J69_RS03390 Genome accession   NZ_AP018777
Coordinates   682300..683643 (-) Length   447 a.a.
NCBI ID   WP_110430717.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-III-6 isolate 13H31     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 677300..688643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J69_RS03360 (CHBNIII6_06400) - 678466..678738 (-) 273 WP_014550417.1 HU family DNA-binding protein -
  K6J69_RS03365 (CHBNIII6_06410) - 678878..679468 (-) 591 WP_110430720.1 YjaG family protein -
  K6J69_RS03370 (CHBNIII6_06420) nudC 679504..680298 (-) 795 WP_110430719.1 NAD(+) diphosphatase -
  K6J69_RS03375 (CHBNIII6_06430) nfuA 680366..680962 (-) 597 WP_105896093.1 Fe-S biogenesis protein NfuA -
  K6J69_RS03380 (CHBNIII6_06440) - 681038..681724 (-) 687 WP_110430718.1 ComF family protein -
  K6J69_RS03385 (CHBNIII6_06450) tnpA 681848..682303 (-) 456 WP_105894588.1 IS200/IS605 family transposase -
  K6J69_RS03390 (CHBNIII6_06460) comE 682300..683643 (-) 1344 WP_110430717.1 type IV pilus secretin PilQ Machinery gene
  K6J69_RS03395 (CHBNIII6_06470) comD 683653..684066 (-) 414 WP_005669241.1 pilus assembly protein PilP Machinery gene
  K6J69_RS03400 (CHBNIII6_06480) comC 684063..684584 (-) 522 WP_110430716.1 competence protein ComC Machinery gene
  K6J69_RS03405 (CHBNIII6_06490) comB 684581..685087 (-) 507 WP_110430715.1 competence protein B Machinery gene
  K6J69_RS03410 (CHBNIII6_06500) comA 685088..685885 (-) 798 WP_110430714.1 pilus assembly protein PilM Machinery gene
  K6J69_RS03415 (CHBNIII6_06510) - 685984..688578 (+) 2595 WP_110430713.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 49277.60 Da        Isoelectric Point: 7.7998

>NTDB_id=71173 K6J69_RS03390 WP_110430717.1 682300..683643(-) (comE) [Haemophilus influenzae strain CHBN-III-6 isolate 13H31]
MKKYFLKCGCFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQQDVNLVIGDILENKISLKLNNIDMPRLLQ
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSSAGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIAGPRLLTTNKKSASIKQGTEIPYVVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PIIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKKLQ

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=71173 K6J69_RS03390 WP_110430717.1 682300..683643(-) (comE) [Haemophilus influenzae strain CHBN-III-6 isolate 13H31]
ATGAAGAAATATTTTTTAAAGTGCGGTTGTTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCCAAAAC
TGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCCCAAACATTGGAACAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATTGGAGATATATTGGAAAACAAGATCTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTACAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGGGTTTATTATTTAAACGGCAGTCAATCTGGCAAAGG
TCAGGTTGCAGGAAATCTTACGACAAATGAACCGCACTTAGTCAGCCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTTCTGCGGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAGGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCAAGCA
TTAAACAGGGGACAGAAATTCCTTACGTCGTGAGCAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCAGTG
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCATTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTAGTAATTTTCGTCACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGCAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

98.427

99.553

0.98
  comE Haemophilus influenzae 86-028NP

97.303

99.553

0.969
  comE Glaesserella parasuis strain SC1401

52.113

95.302

0.497
  pilQ Vibrio campbellii strain DS40M4

42.482

93.736

0.398
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.505

92.17

0.383
  pilQ Vibrio cholerae strain A1552

41.505

92.17

0.383

Multiple sequence alignment