Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIB63_RS22800 Genome accession   NZ_CP116194
Coordinates   4682992..4683582 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain DETEC-E1005     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4677992..4688582
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIB63_RS22785 (PIB63_22785) uhpT 4678632..4680023 (-) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -
  PIB63_RS22790 (PIB63_22790) uhpC 4680161..4681480 (-) 1320 WP_001298006.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  PIB63_RS22795 (PIB63_22795) uhpB 4681490..4682992 (-) 1503 WP_001314238.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  PIB63_RS22800 (PIB63_22800) letA 4682992..4683582 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  PIB63_RS22805 (PIB63_22805) ilvN 4683655..4683945 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  PIB63_RS22810 (PIB63_22810) ilvB 4683949..4685637 (-) 1689 WP_000168476.1 acetolactate synthase large subunit -
  PIB63_RS22815 (PIB63_22815) ivbL 4685743..4685841 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  PIB63_RS22820 (PIB63_22820) ysdE 4686086..4686160 (-) 75 WP_211180519.1 protein YsdE -
  PIB63_RS22825 (PIB63_22825) emrD 4686242..4687426 (+) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  PIB63_RS22830 (PIB63_22830) yidF 4687434..4687931 (-) 498 WP_000148045.1 radical SAM protein -
  PIB63_RS22835 (PIB63_22835) yidG 4687928..4688290 (-) 363 WP_001113432.1 DUF202 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=709110 PIB63_RS22800 WP_000633668.1 4682992..4683582(-) (letA) [Escherichia coli strain DETEC-E1005]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=709110 PIB63_RS22800 WP_000633668.1 4682992..4683582(-) (letA) [Escherichia coli strain DETEC-E1005]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTTATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCACCGAAAACGGTACATGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378