Detailed information NTG0070895

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: H7680_RS00355
• Genome accession: NZ_AP023394
• Coordinates: 56711..57622 (+)
• Length: 303 a.a.
• NCBI ID: WP_003060893.1
• Uniprot ID: A0ABU0A8X5
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain 159
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 51711..62622

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7680_RS00330 (SDSE159_00330)	purE	52212..52700 (+)	489	WP_003055559.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
H7680_RS00335 (SDSE159_00340)	purK	52687..53760 (+)	1074	WP_003055561.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
H7680_RS00340 (SDSE159_00350)	-	53770..55026 (+)	1257	WP_003055555.1	DUF4041 domain-containing protein	-
H7680_RS00345 (SDSE159_00360)	-	55019..55228 (+)	210	WP_014611912.1	hypothetical protein	-
H7680_RS00350 (SDSE159_00370)	purB	55277..56569 (+)	1293	WP_003056595.1	adenylosuccinate lyase	-
H7680_RS00355 (SDSE159_00380)	comR	56711..57622 (+)	912	WP_003060893.1	XRE family transcriptional regulator	Regulator
H7680_RS10365	comS	57709..57807 (+)	99	WP_014611913.1	quorum-sensing system DWW-type pheromone	Regulator
H7680_RS00360 (SDSE159_00390)	ruvB	57841..58839 (+)	999	WP_003059357.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
H7680_RS00365 (SDSE159_00400)	-	58974..59405 (+)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
H7680_RS00370 (SDSE159_00410)	-	59434..59835 (+)	402	WP_003049089.1	MORN repeat-containing protein	-
H7680_RS00375 (SDSE159_00420)	-	59832..61607 (+)	1776	WP_003059359.1	acyltransferase family protein	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35995.62 Da
• Isoelectric Point: 4.7392

>NTDB_id=70895 H7680_RS00355 WP_003060893.1 56711..57622(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=70895 H7680_RS00355 WP_003060893.1 56711..57622(+) (comR) [Streptococcus dysgalactiae subsp. equisimilis strain 159]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTGTCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	46.154	98.68	0.455
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363