Detailed information NTG0070802

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: H7678_RS00750
• Genome accession: NZ_AP023393
• Coordinates: 121907..122347 (+)
• Length: 146 a.a.
• NCBI ID: WP_003061780.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain 89
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 116907..127347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7678_RS00720 (SDSE89_00950)	-	118588..118953 (+)	366	WP_003055257.1	DUF1033 family protein	-
H7678_RS00725 (SDSE89_00960)	comGA/cglA	119034..119975 (+)	942	WP_003062163.1	competence type IV pilus ATPase ComGA	Machinery gene
H7678_RS00730 (SDSE89_00970)	comGB	119911..120942 (+)	1032	WP_050807598.1	competence type IV pilus assembly protein ComGB	Machinery gene
H7678_RS00735 (SDSE89_00980)	comGC	120944..121270 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
H7678_RS00740	comGD	121245..121673 (+)	429	WP_037589807.1	competence type IV pilus minor pilin ComGD	Machinery gene
H7678_RS00745 (SDSE89_00990)	comGE	121681..121926 (+)	246	WP_003049263.1	competence type IV pilus minor pilin ComGE	Machinery gene
H7678_RS00750 (SDSE89_01000)	comGF	121907..122347 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
H7678_RS00755 (SDSE89_01010)	comGG	122370..122699 (+)	330	WP_003062466.1	competence type IV pilus minor pilin ComGG	-
H7678_RS00760 (SDSE89_01020)	comGH	122762..123715 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
H7678_RS00765 (SDSE89_01030)	-	123774..124970 (+)	1197	WP_003058485.1	acetate kinase	-
H7678_RS00770 (SDSE89_01040)	-	125276..125482 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
H7678_RS00775 (SDSE89_01050)	-	125585..126265 (+)	681	WP_003060329.1	type II CAAX endopeptidase family protein	-
H7678_RS00780 (SDSE89_01060)	-	126283..126720 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16969.55 Da
• Isoelectric Point: 10.6305

>NTDB_id=70802 H7678_RS00750 WP_003061780.1 121907..122347(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=70802 H7678_RS00750 WP_003061780.1 121907..122347(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTGCTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.921	95.205	0.466
comGF	Streptococcus mutans UA140	48.201	95.205	0.459
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411