Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE   Type   Machinery gene
Locus tag   H7678_RS00745 Genome accession   NZ_AP023393
Coordinates   121681..121926 (+) Length   81 a.a.
NCBI ID   WP_003049263.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain 89     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 116681..126926
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7678_RS00720 (SDSE89_00950) - 118588..118953 (+) 366 WP_003055257.1 DUF1033 family protein -
  H7678_RS00725 (SDSE89_00960) comGA/cglA 119034..119975 (+) 942 WP_003062163.1 competence type IV pilus ATPase ComGA Machinery gene
  H7678_RS00730 (SDSE89_00970) comGB 119911..120942 (+) 1032 WP_050807598.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7678_RS00735 (SDSE89_00980) comGC 120944..121270 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  H7678_RS00740 comGD 121245..121673 (+) 429 WP_037589807.1 competence type IV pilus minor pilin ComGD Machinery gene
  H7678_RS00745 (SDSE89_00990) comGE 121681..121926 (+) 246 WP_003049263.1 competence type IV pilus minor pilin ComGE Machinery gene
  H7678_RS00750 (SDSE89_01000) comGF 121907..122347 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7678_RS00755 (SDSE89_01010) comGG 122370..122699 (+) 330 WP_003062466.1 competence type IV pilus minor pilin ComGG -
  H7678_RS00760 (SDSE89_01020) comGH 122762..123715 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  H7678_RS00765 (SDSE89_01030) - 123774..124970 (+) 1197 WP_003058485.1 acetate kinase -
  H7678_RS00770 (SDSE89_01040) - 125276..125482 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -
  H7678_RS00775 (SDSE89_01050) - 125585..126265 (+) 681 WP_003060329.1 type II CAAX endopeptidase family protein -
  H7678_RS00780 (SDSE89_01060) - 126283..126720 (+) 438 WP_012766452.1 hypothetical protein -

Sequence


Protein


Download         Length: 81 a.a.        Molecular weight: 9193.76 Da        Isoelectric Point: 10.1569

>NTDB_id=70801 H7678_RS00745 WP_003049263.1 121681..121926(+) (comGE) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
MATGLLVAIVILVLTSLKQSQTRLTYYRSQQEKLNLALMAVQTGQASLNMNDCRLTVSRTEKTLIVRDQEGEVIRIEKKD
R

Nucleotide


Download         Length: 246 bp        

>NTDB_id=70801 H7678_RS00745 WP_003049263.1 121681..121926(+) (comGE) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
ATGGCAACAGGCCTCCTCGTGGCTATTGTCATACTGGTTCTAACGAGTTTGAAGCAAAGTCAGACAAGGTTGACATATTA
TCGCAGCCAACAAGAAAAGCTCAACCTAGCTCTGATGGCAGTACAAACTGGTCAAGCGTCTCTCAATATGAATGATTGTC
GTCTGACGGTTTCACGCACAGAAAAAACACTTATCGTTAGGGATCAGGAAGGAGAGGTTATTAGAATTGAAAAAAAGGAC
AGGTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

41.772

97.531

0.407

  comGE Streptococcus mutans UA159

41.772

97.531

0.407


Multiple sequence alignment