Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FGCSD_RS01145 Genome accession   NZ_AP018726
Coordinates   204188..205219 (+) Length   343 a.a.
NCBI ID   WP_129556365.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain Kdys0611     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 199188..210219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGCSD_RS01135 (FGCSD_0178) - 202865..203230 (+) 366 WP_129555183.1 DUF1033 family protein -
  FGCSD_RS01140 (FGCSD_0179) comYA 203311..204252 (+) 942 WP_129555184.1 competence type IV pilus ATPase ComGA Machinery gene
  FGCSD_RS01145 (FGCSD_0180) comYB 204188..205219 (+) 1032 WP_129556365.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGCSD_RS01150 (FGCSD_0181) comYC 205221..205547 (+) 327 WP_111714771.1 competence type IV pilus major pilin ComGC Machinery gene
  FGCSD_RS11205 (FGCSD_0182) comGD 205522..205950 (+) 429 WP_129555185.1 competence type IV pilus minor pilin ComGD -
  FGCSD_RS01160 (FGCSD_0183) comGE 205907..206203 (+) 297 WP_129555186.1 competence type IV pilus minor pilin ComGE -
  FGCSD_RS01165 (FGCSD_0184) comGF 206184..206624 (+) 441 WP_129555187.1 competence type IV pilus minor pilin ComGF -
  FGCSD_RS01170 (FGCSD_0185) comGG 206602..206976 (+) 375 WP_129555188.1 competence type IV pilus minor pilin ComGG -
  FGCSD_RS01175 (FGCSD_0186) comYH 207039..207992 (+) 954 WP_129555189.1 class I SAM-dependent methyltransferase Machinery gene
  FGCSD_RS01180 (FGCSD_0187) - 208051..209247 (+) 1197 WP_129555190.1 acetate kinase -
  FGCSD_RS01185 (FGCSD_0188) - 209553..209760 (+) 208 Protein_180 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38937.35 Da        Isoelectric Point: 8.9053

>NTDB_id=70560 FGCSD_RS01145 WP_129556365.1 204188..205219(+) (comYB) [Streptococcus dysgalactiae strain Kdys0611]
MTFLQQDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLTEIIAFLTKSHLIPEPYVLRMEEVLLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMMLGLRHYVMPQLEAQNQLTIFLTH
FPAIFFGLILFIGVLLGGIWLHWRSQSRLKLFTHLSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMAMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWAQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=70560 FGCSD_RS01145 WP_129556365.1 204188..205219(+) (comYB) [Streptococcus dysgalactiae strain Kdys0611]
ATGACCTTCTTGCAGCAGGACATCTCAGTCCGGAGCAAGCAAGGCTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGACTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTTCGCATGGAAGAAGTACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATGTTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAGCTCAAAATCAGCTTACTATTTTTCTCACTCAT
TTTCCAGCTATTTTCTTTGGTCTTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTACTCACCTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGGCCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTCAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAATTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGGCTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.277

98.834

0.536
  comYB Streptococcus mutans UA159

54.277

98.834

0.536
  comYB Streptococcus gordonii str. Challis substr. CH1

49.263

98.834

0.487
  comGB/cglB Streptococcus mitis NCTC 12261

46.567

97.668

0.455
  comGB/cglB Streptococcus mitis SK321

45.946

97.085

0.446
  comGB/cglB Streptococcus pneumoniae Rx1

44.444

97.085

0.431
  comGB/cglB Streptococcus pneumoniae D39

44.444

97.085

0.431
  comGB/cglB Streptococcus pneumoniae R6

44.444

97.085

0.431
  comGB/cglB Streptococcus pneumoniae TIGR4

44.444

97.085

0.431
  comGB Lactococcus lactis subsp. cremoris KW2

43.363

98.834

0.429

Multiple sequence alignment