Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FGCSD_RS01140 Genome accession   NZ_AP018726
Coordinates   203311..204252 (+) Length   313 a.a.
NCBI ID   WP_129555184.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain Kdys0611     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 198311..209252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGCSD_RS01130 (FGCSD_0177) rpoC 199020..202661 (+) 3642 WP_111714766.1 DNA-directed RNA polymerase subunit beta' -
  FGCSD_RS01135 (FGCSD_0178) - 202865..203230 (+) 366 WP_129555183.1 DUF1033 family protein -
  FGCSD_RS01140 (FGCSD_0179) comYA 203311..204252 (+) 942 WP_129555184.1 competence type IV pilus ATPase ComGA Machinery gene
  FGCSD_RS01145 (FGCSD_0180) comYB 204188..205219 (+) 1032 WP_129556365.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGCSD_RS01150 (FGCSD_0181) comYC 205221..205547 (+) 327 WP_111714771.1 competence type IV pilus major pilin ComGC Machinery gene
  FGCSD_RS11205 (FGCSD_0182) comGD 205522..205950 (+) 429 WP_129555185.1 competence type IV pilus minor pilin ComGD -
  FGCSD_RS01160 (FGCSD_0183) comGE 205907..206203 (+) 297 WP_129555186.1 competence type IV pilus minor pilin ComGE -
  FGCSD_RS01165 (FGCSD_0184) comGF 206184..206624 (+) 441 WP_129555187.1 competence type IV pilus minor pilin ComGF -
  FGCSD_RS01170 (FGCSD_0185) comGG 206602..206976 (+) 375 WP_129555188.1 competence type IV pilus minor pilin ComGG -
  FGCSD_RS01175 (FGCSD_0186) comYH 207039..207992 (+) 954 WP_129555189.1 class I SAM-dependent methyltransferase Machinery gene
  FGCSD_RS01180 (FGCSD_0187) - 208051..209247 (+) 1197 WP_129555190.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35248.39 Da        Isoelectric Point: 7.0192

>NTDB_id=70559 FGCSD_RS01140 WP_129555184.1 203311..204252(+) (comYA) [Streptococcus dysgalactiae strain Kdys0611]
MVQALARSILKEAEQMQAQDIYILPKEDQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGEDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMYQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLAAGHLSPEQARLEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=70559 FGCSD_RS01140 WP_129555184.1 203311..204252(+) (comYA) [Streptococcus dysgalactiae strain Kdys0611]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATGCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AGATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGAAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGAAATTACCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACACTACTGGTTTGACGGACTGAAAACAGTTGCACGTCAGATTGGAGGCCGAGGAC
TCTATCTTTTTGCTGGTCCAGTCGGATCAGGCAAAACGACTTTGATGTACCAATTGATTGCTGATTATTATCAGGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAGGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTTCATGCCAAAAGTATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAGCAGGACATCTCAGTCCGGAGCAAGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

62.058

99.361

0.617
  comYA Streptococcus mutans UA159

62.058

99.361

0.617
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comYA Streptococcus gordonii str. Challis substr. CH1

60.772

99.361

0.604
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.361

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.486

99.361

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

52.09

99.361

0.518
  comGA Latilactobacillus sakei subsp. sakei 23K

39.249

93.61

0.367

Multiple sequence alignment