NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	NLY78_RS07075	Genome accession	NZ_CP100435
Coordinates	1439675..1440265 (-)	Length	196 a.a.
NCBI ID	WP_002937303.1	Uniprot ID	A0A0K2E545
Organism	Streptococcus suis strain DE609B
Function	degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1434675..1445265

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NLY78_RS07050 (NLY78_07045)	-	1435159..1435923 (-)	765	WP_002937291.1	ABC transporter ATP-binding protein	-
NLY78_RS07055 (NLY78_07050)	-	1435923..1436870 (-)	948	WP_002937293.1	branched-chain amino acid ABC transporter permease	-
NLY78_RS07060 (NLY78_07055)	-	1436873..1437760 (-)	888	WP_012027482.1	branched-chain amino acid ABC transporter permease	-
NLY78_RS07065 (NLY78_07060)	-	1437976..1439145 (-)	1170	WP_012775268.1	ABC transporter substrate-binding protein	-
NLY78_RS07070 (NLY78_07065)	-	1439276..1439548 (-)	273	WP_002937299.1	YlbG family protein	-
NLY78_RS07075 (NLY78_07070)	clpP	1439675..1440265 (-)	591	WP_002937303.1	ATP-dependent Clp protease proteolytic subunit	Regulator
NLY78_RS07080 (NLY78_07075)	upp	1440382..1441011 (-)	630	WP_012027487.1	uracil phosphoribosyltransferase	-
NLY78_RS07085 (NLY78_07080)	-	1441091..1442707 (-)	1617	WP_074392928.1	alpha-glucosidase	-
NLY78_RS07090 (NLY78_07085)	gtfA	1442780..1444228 (-)	1449	WP_012027490.1	sucrose phosphorylase	-
NLY78_RS07095 (NLY78_07090)	-	1444299..1445129 (-)	831	WP_002937312.1	carbohydrate ABC transporter permease	-

Sequence

Protein

Download Length: 196 a.a. Molecular weight: 21494.74 Da Isoelectric Point: 5.7110

                                >NTDB_id=705378 NLY78_RS07075 WP_002937303.1 1439675..1440265(-) (clpP) [Streptococcus suis strain DE609B]

MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGLAIVDTMN

FIKADVQTIVMGTAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKILADNSGK

TVKQIHKDAERDYWMSAEETLAYGFIDQIMDNTKVK

Nucleotide

Download Length: 591 bp

                                >NTDB_id=705378 NLY78_RS07075 WP_002937303.1 1439675..1440265(-) (clpP) [Streptococcus suis strain DE609B]

ATGATTCCAGTAGTTATTGAACAAACTAGCCGTGGTGAGCGTTCTTATGATATTTACTCACGCCTTTTGAAAGACCGTAT

TATCATGTTGACAGGACCAGTTGAGGACAACATGGCAAACTCTATCATTGCACAATTGCTTTTCCTTGATGCCCAAGACC

CTACAAAGGATATTTACCTCTATGTTAATACGCCAGGAGGATCGGTGTCAGCAGGTCTTGCCATTGTAGACACGATGAAT

TTCATTAAAGCTGATGTTCAAACCATCGTTATGGGAACAGCTGCGAGCATGGGAACCATCATTGCATCAAGCGGTGCCAA

GGGCAAACGTTTCATGTTGCCAAATGCAGAGTACATGATTCACCAGCCAATGGGTGGAACTGGTGGTGGTACTCAGCAAA

CAGATATGGCTATTGCTGCAGAACACCTATTAAAAACACGTAATAAGCTAGAAAAAATCTTGGCAGACAACTCAGGTAAG

ACAGTCAAGCAAATCCACAAGGATGCGGAACGTGATTACTGGATGTCAGCTGAAGAAACCTTGGCTTACGGATTTATTGA

CCAGATTATGGACAATACAAAAGTCAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0K2E545

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Streptococcus pyogenes JRS4	92.347	100	0.923
clpP	Streptococcus pyogenes MGAS315	92.347	100	0.923
clpP	Streptococcus mutans UA159	90.306	100	0.903
clpP	Streptococcus pneumoniae R6	88.776	100	0.888
clpP	Streptococcus pneumoniae Rx1	88.776	100	0.888
clpP	Streptococcus pneumoniae D39	88.776	100	0.888
clpP	Streptococcus pneumoniae TIGR4	88.776	100	0.888
clpP	Streptococcus thermophilus LMG 18311	88.776	100	0.888
clpP	Streptococcus thermophilus LMD-9	88.776	100	0.888
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	84.184	100	0.842
clpP	Lactococcus lactis subsp. cremoris KW2	83.673	100	0.837
clpP	Bacillus subtilis subsp. subtilis str. 168	58.163	100	0.582
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.549	98.469	0.577

Detailed information NTG0705378