Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   H7676_RS00665 Genome accession   NZ_AP023390
Coordinates   103893..104321 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain KUN-0014944     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98893..109321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7676_RS00645 (KUN4944_00790) - 101209..101574 (+) 366 WP_002986560.1 DUF1033 family protein -
  H7676_RS00650 (KUN4944_00800) comGA 101667..102620 (+) 954 WP_184492312.1 competence type IV pilus ATPase ComGA Machinery gene
  H7676_RS00655 (KUN4944_00810) comGB 102556..103590 (+) 1035 WP_226316548.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7676_RS00660 (KUN4944_00820) comGC 103592..103918 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  H7676_RS00665 (KUN4944_00830) comGD 103893..104321 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  H7676_RS00670 (KUN4944_00840) comGE 104278..104562 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  H7676_RS00675 (KUN4944_00850) comGF 104555..104989 (+) 435 WP_020904833.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7676_RS00680 (KUN4944_00860) comGG 104973..105299 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  H7676_RS00685 (KUN4944_00870) comGH 105397..106350 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  H7676_RS00690 (KUN4944_00880) - 106409..107605 (+) 1197 WP_020904834.1 acetate kinase -
  H7676_RS00695 - 107792..108100 (+) 309 Protein_90 hypothetical protein -
  H7676_RS00700 (KUN4944_00890) proC 108183..108953 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=70517 H7676_RS00665 WP_002986548.1 103893..104321(+) (comGD) [Streptococcus pyogenes strain KUN-0014944]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=70517 H7676_RS00665 WP_002986548.1 103893..104321(+) (comGD) [Streptococcus pyogenes strain KUN-0014944]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366