Detailed information
Bioinformatically predicted
Overview
| Name | clpP | Type | Regulator |
| Locus tag | NLY35_RS08020 | Genome accession | NZ_CP100418 |
| Coordinates | 1607276..1607887 (-) | Length | 203 a.a. |
| NCBI ID | WP_223375679.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain STC104 | ||
| Function | degradation of ComX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1560883..1607866 | 1607276..1607887 | flank | -590 |
Gene organization within MGE regions
Location: 1560883..1607887
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NLY35_RS07675 (NLY35_07675) | - | 1560883..1561620 (-) | 738 | WP_014636660.1 | PlySs2 family phage lysin | - |
| NLY35_RS07680 (NLY35_07680) | - | 1561604..1561954 (-) | 351 | WP_002937841.1 | phage holin | - |
| NLY35_RS07685 (NLY35_07685) | - | 1561957..1562256 (-) | 300 | WP_014636661.1 | hypothetical protein | - |
| NLY35_RS07690 (NLY35_07690) | - | 1562260..1562604 (-) | 345 | WP_002937844.1 | hypothetical protein | - |
| NLY35_RS07695 (NLY35_07695) | - | 1562607..1562825 (-) | 219 | WP_002937846.1 | hypothetical protein | - |
| NLY35_RS07700 (NLY35_07700) | - | 1562834..1568176 (-) | 5343 | WP_204101658.1 | phage tail spike protein | - |
| NLY35_RS07705 (NLY35_07705) | - | 1568173..1568868 (-) | 696 | WP_002937853.1 | adenylosuccinate synthetase | - |
| NLY35_RS07710 (NLY35_07710) | - | 1568868..1571450 (-) | 2583 | WP_044768633.1 | phage tail protein | - |
| NLY35_RS07715 (NLY35_07715) | - | 1571440..1571823 (-) | 384 | WP_002937861.1 | DUF5361 domain-containing protein | - |
| NLY35_RS07720 (NLY35_07720) | - | 1571820..1572098 (-) | 279 | WP_024379224.1 | hypothetical protein | - |
| NLY35_RS07725 (NLY35_07725) | - | 1572109..1572696 (-) | 588 | WP_204101659.1 | phage tail protein | - |
| NLY35_RS07730 (NLY35_07730) | - | 1572712..1573047 (-) | 336 | WP_002937874.1 | hypothetical protein | - |
| NLY35_RS07735 (NLY35_07735) | - | 1573044..1573283 (-) | 240 | WP_002937877.1 | hypothetical protein | - |
| NLY35_RS07740 (NLY35_07740) | - | 1573276..1573614 (-) | 339 | WP_002937879.1 | hypothetical protein | - |
| NLY35_RS07745 (NLY35_07745) | - | 1573601..1573996 (-) | 396 | WP_002937880.1 | phage Gp19/Gp15/Gp42 family protein | - |
| NLY35_RS07750 (NLY35_07750) | - | 1574000..1574224 (-) | 225 | WP_002937881.1 | HeH/LEM domain-containing protein | - |
| NLY35_RS07755 (NLY35_07755) | - | 1574226..1575128 (-) | 903 | WP_002937882.1 | phage major capsid protein | - |
| NLY35_RS07760 (NLY35_07760) | - | 1575143..1575613 (-) | 471 | WP_002937883.1 | DUF4355 domain-containing protein | - |
| NLY35_RS07765 (NLY35_07765) | - | 1575696..1577111 (-) | 1416 | WP_002937884.1 | terminase | - |
| NLY35_RS11305 | - | 1577256..1577387 (-) | 132 | WP_002937886.1 | hypothetical protein | - |
| NLY35_RS07770 (NLY35_07770) | - | 1577456..1577668 (-) | 213 | WP_002937901.1 | hypothetical protein | - |
| NLY35_RS07775 (NLY35_07775) | - | 1577665..1578744 (-) | 1080 | WP_002937903.1 | hypothetical protein | - |
| NLY35_RS07780 (NLY35_07780) | - | 1578737..1580002 (-) | 1266 | WP_002937907.1 | phage portal protein | - |
| NLY35_RS07785 (NLY35_07785) | - | 1579999..1580361 (-) | 363 | WP_002937910.1 | hypothetical protein | - |
| NLY35_RS07790 (NLY35_07790) | - | 1580440..1580787 (-) | 348 | WP_002937914.1 | HNH endonuclease | - |
| NLY35_RS07795 (NLY35_07795) | - | 1580884..1581318 (-) | 435 | WP_002937915.1 | DUF1492 domain-containing protein | - |
| NLY35_RS07800 (NLY35_07800) | - | 1581395..1581661 (-) | 267 | WP_226314725.1 | hypothetical protein | - |
| NLY35_RS07805 (NLY35_07805) | - | 1581658..1581927 (-) | 270 | WP_002937922.1 | hypothetical protein | - |
| NLY35_RS07810 (NLY35_07810) | - | 1581927..1582103 (-) | 177 | WP_002937925.1 | hypothetical protein | - |
| NLY35_RS07815 (NLY35_07815) | - | 1582103..1582336 (-) | 234 | WP_002937935.1 | hypothetical protein | - |
| NLY35_RS07820 (NLY35_07820) | - | 1582352..1582654 (-) | 303 | WP_002937939.1 | DUF1372 family protein | - |
| NLY35_RS07825 (NLY35_07825) | - | 1582664..1583182 (-) | 519 | WP_002937943.1 | hypothetical protein | - |
| NLY35_RS07830 (NLY35_07830) | - | 1583179..1583511 (-) | 333 | WP_002937944.1 | hypothetical protein | - |
| NLY35_RS07835 (NLY35_07835) | - | 1583601..1583789 (-) | 189 | WP_254377503.1 | hypothetical protein | - |
| NLY35_RS07840 (NLY35_07840) | - | 1583824..1584198 (-) | 375 | WP_002937949.1 | hypothetical protein | - |
| NLY35_RS07845 (NLY35_07845) | ssb | 1584226..1584687 (-) | 462 | WP_002937951.1 | single-stranded DNA-binding protein | Machinery gene |
| NLY35_RS07850 (NLY35_07850) | - | 1584790..1584969 (-) | 180 | WP_002937955.1 | hypothetical protein | - |
| NLY35_RS07855 (NLY35_07855) | - | 1584959..1585285 (-) | 327 | WP_002937956.1 | hypothetical protein | - |
| NLY35_RS07860 (NLY35_07860) | - | 1585295..1585564 (-) | 270 | WP_002937957.1 | hypothetical protein | - |
| NLY35_RS07865 (NLY35_07865) | - | 1585567..1586595 (-) | 1029 | WP_172055947.1 | DUF1351 domain-containing protein | - |
| NLY35_RS07870 (NLY35_07870) | bet | 1586605..1587375 (-) | 771 | WP_014636675.1 | phage recombination protein Bet | - |
| NLY35_RS07875 (NLY35_07875) | - | 1587372..1587551 (-) | 180 | WP_004195116.1 | hypothetical protein | - |
| NLY35_RS11310 | - | 1587551..1587679 (-) | 129 | WP_014636676.1 | hypothetical protein | - |
| NLY35_RS07880 (NLY35_07880) | - | 1587690..1587833 (-) | 144 | WP_014636677.1 | hypothetical protein | - |
| NLY35_RS07885 (NLY35_07885) | - | 1588092..1588457 (-) | 366 | WP_004194647.1 | hypothetical protein | - |
| NLY35_RS07890 (NLY35_07890) | - | 1588510..1588734 (-) | 225 | WP_004194648.1 | hypothetical protein | - |
| NLY35_RS07895 (NLY35_07895) | - | 1588715..1588972 (-) | 258 | WP_014636678.1 | hypothetical protein | - |
| NLY35_RS07900 (NLY35_07900) | - | 1588969..1589244 (-) | 276 | WP_014636679.1 | hypothetical protein | - |
| NLY35_RS07905 (NLY35_07905) | - | 1589327..1590037 (-) | 711 | WP_014636680.1 | phage antirepressor KilAC domain-containing protein | - |
| NLY35_RS07910 (NLY35_07910) | - | 1590091..1590780 (+) | 690 | WP_014636681.1 | DUF4145 domain-containing protein | - |
| NLY35_RS07915 (NLY35_07915) | - | 1590876..1591097 (-) | 222 | WP_004195135.1 | hypothetical protein | - |
| NLY35_RS07920 (NLY35_07920) | - | 1591150..1591377 (-) | 228 | WP_024414969.1 | hypothetical protein | - |
| NLY35_RS07925 (NLY35_07925) | - | 1591384..1591575 (-) | 192 | WP_172051330.1 | helix-turn-helix transcriptional regulator | - |
| NLY35_RS11315 | - | 1591718..1591846 (+) | 129 | WP_255199034.1 | hypothetical protein | - |
| NLY35_RS07930 (NLY35_07930) | - | 1591836..1592219 (-) | 384 | WP_226314723.1 | ImmA/IrrE family metallo-endopeptidase | - |
| NLY35_RS07935 (NLY35_07935) | - | 1592290..1592484 (-) | 195 | WP_204108029.1 | hypothetical protein | - |
| NLY35_RS07940 (NLY35_07940) | - | 1592583..1593347 (+) | 765 | WP_172051331.1 | XRE family transcriptional regulator | - |
| NLY35_RS07945 (NLY35_07945) | - | 1593523..1593957 (+) | 435 | WP_004194675.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| NLY35_RS07950 (NLY35_07950) | - | 1594083..1595177 (+) | 1095 | WP_201326760.1 | tyrosine-type recombinase/integrase | - |
| NLY35_RS07960 (NLY35_07960) | - | 1595484..1597508 (-) | 2025 | WP_029743814.1 | bifunctional UDP-sugar hydrolase/5'-nucleotidase | - |
| NLY35_RS07965 (NLY35_07965) | - | 1597648..1598601 (-) | 954 | WP_024376800.1 | IS30 family transposase | - |
| NLY35_RS07970 (NLY35_07970) | sodA | 1599015..1599620 (-) | 606 | WP_013730459.1 | superoxide dismutase SodA | - |
| NLY35_RS07975 (NLY35_07975) | holA | 1599733..1600764 (-) | 1032 | WP_024417674.1 | DNA polymerase III subunit delta | - |
| NLY35_RS07980 (NLY35_07980) | - | 1600914..1601504 (-) | 591 | WP_024402863.1 | hypothetical protein | - |
| NLY35_RS07985 (NLY35_07985) | - | 1601617..1601979 (-) | 363 | Protein_1533 | epoxyqueuosine reductase QueH | - |
| NLY35_RS07990 (NLY35_07990) | - | 1602069..1602779 (-) | 711 | WP_002937288.1 | ABC transporter ATP-binding protein | - |
| NLY35_RS07995 (NLY35_07995) | - | 1602779..1603543 (-) | 765 | WP_029176900.1 | ABC transporter ATP-binding protein | - |
| NLY35_RS08000 (NLY35_08000) | - | 1603543..1604490 (-) | 948 | WP_024378398.1 | branched-chain amino acid ABC transporter permease | - |
| NLY35_RS08005 (NLY35_08005) | - | 1604493..1605380 (-) | 888 | WP_204101587.1 | branched-chain amino acid ABC transporter permease | - |
| NLY35_RS08010 (NLY35_08010) | - | 1605576..1606745 (-) | 1170 | WP_044760026.1 | ABC transporter substrate-binding protein | - |
| NLY35_RS08015 (NLY35_08015) | - | 1606877..1607149 (-) | 273 | WP_002937299.1 | YlbG family protein | - |
| NLY35_RS08020 (NLY35_08020) | clpP | 1607276..1607887 (-) | 612 | WP_223375679.1 | ATP-dependent Clp protease proteolytic subunit | Regulator |
Sequence
Protein
Download Length: 203 a.a. Molecular weight: 22345.73 Da Isoelectric Point: 6.7324
>NTDB_id=704984 NLY35_RS08020 WP_223375679.1 1607276..1607887(-) (clpP) [Streptococcus suis strain STC104]
MSKRSNFMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGL
AIVDTMNFIKADVQTIVMGTAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKI
LADNSGKTVKQIHKDAERDYWMSAEETLAYGFIDQIMDNTKVK
MSKRSNFMIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDPTKDIYLYVNTPGGSVSAGL
AIVDTMNFIKADVQTIVMGTAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNKLEKI
LADNSGKTVKQIHKDAERDYWMSAEETLAYGFIDQIMDNTKVK
Nucleotide
Download Length: 612 bp
>NTDB_id=704984 NLY35_RS08020 WP_223375679.1 1607276..1607887(-) (clpP) [Streptococcus suis strain STC104]
ATCTCGAAAAGGAGTAATTTTATGATTCCAGTAGTTATTGAACAAACTAGCCGTGGTGAACGTTCTTATGATATTTATTC
ACGCCTATTGAAAGATCGTATTATCATGCTGACAGGACCAGTTGAGGATAATATGGCAAACTCTATCATTGCACAATTGC
TTTTCCTTGATGCCCAAGACCCTACAAAGGATATTTACCTCTATGTTAACACGCCAGGAGGATCGGTGTCAGCAGGTCTT
GCCATTGTAGACACGATGAATTTCATTAAAGCTGATGTGCAAACCATCGTCATGGGGACAGCTGCTAGCATGGGTACAAT
TATCGCTTCAAGTGGTGCCAAAGGCAAACGTTTCATGTTGCCAAATGCGGAATACATGATTCACCAACCAATGGGTGGAA
CTGGTGGCGGTACTCAGCAAACGGATATGGCCATTGCTGCAGAACACCTATTAAAAACACGTAATAAGCTAGAAAAAATC
TTGGCAGACAACTCAGGTAAGACAGTCAAGCAAATCCACAAGGATGCGGAACGTGATTACTGGATGTCAGCTGAAGAAAC
CTTGGCTTACGGATTTATTGACCAGATTATGGACAATACAAAAGTCAAATAA
ATCTCGAAAAGGAGTAATTTTATGATTCCAGTAGTTATTGAACAAACTAGCCGTGGTGAACGTTCTTATGATATTTATTC
ACGCCTATTGAAAGATCGTATTATCATGCTGACAGGACCAGTTGAGGATAATATGGCAAACTCTATCATTGCACAATTGC
TTTTCCTTGATGCCCAAGACCCTACAAAGGATATTTACCTCTATGTTAACACGCCAGGAGGATCGGTGTCAGCAGGTCTT
GCCATTGTAGACACGATGAATTTCATTAAAGCTGATGTGCAAACCATCGTCATGGGGACAGCTGCTAGCATGGGTACAAT
TATCGCTTCAAGTGGTGCCAAAGGCAAACGTTTCATGTTGCCAAATGCGGAATACATGATTCACCAACCAATGGGTGGAA
CTGGTGGCGGTACTCAGCAAACGGATATGGCCATTGCTGCAGAACACCTATTAAAAACACGTAATAAGCTAGAAAAAATC
TTGGCAGACAACTCAGGTAAGACAGTCAAGCAAATCCACAAGGATGCGGAACGTGATTACTGGATGTCAGCTGAAGAAAC
CTTGGCTTACGGATTTATTGACCAGATTATGGACAATACAAAAGTCAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpP | Streptococcus pyogenes JRS4 |
92.347 |
96.552 |
0.892 |
| clpP | Streptococcus pyogenes MGAS315 |
92.347 |
96.552 |
0.892 |
| clpP | Streptococcus mutans UA159 |
90.306 |
96.552 |
0.872 |
| clpP | Streptococcus thermophilus LMD-9 |
88.776 |
96.552 |
0.857 |
| clpP | Streptococcus thermophilus LMG 18311 |
88.776 |
96.552 |
0.857 |
| clpP | Streptococcus pneumoniae R6 |
89.231 |
96.059 |
0.857 |
| clpP | Streptococcus pneumoniae Rx1 |
89.231 |
96.059 |
0.857 |
| clpP | Streptococcus pneumoniae D39 |
89.231 |
96.059 |
0.857 |
| clpP | Streptococcus pneumoniae TIGR4 |
89.231 |
96.059 |
0.857 |
| clpP | Lactococcus lactis subsp. lactis strain DGCC12653 |
83.756 |
97.044 |
0.813 |
| clpP | Lactococcus lactis subsp. cremoris KW2 |
83.249 |
97.044 |
0.808 |
| clpP | Bacillus subtilis subsp. subtilis str. 168 |
58.163 |
96.552 |
0.562 |
| clpP | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
58.549 |
95.074 |
0.557 |