Detailed information NTG0070409

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: H7674_RS08575
• Genome accession: NZ_AP023388
• Coordinates: 1765280..1766047 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NIH35
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1760280..1771047

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7674_RS08560 (SPNIH35_16420)	hexB	1760798..1762780 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
H7674_RS08565 (SPNIH35_16430)	-	1762875..1764026 (-)	1152	WP_003058754.1	tyrosine-type recombinase/integrase	-
H7674_RS09235	-	1764275..1764418 (+)	144	WP_011185066.1	putative holin-like toxin	-
H7674_RS08575 (SPNIH35_16440)	irvR	1765280..1766047 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
H7674_RS08580 (SPNIH35_16450)	-	1766201..1766407 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
H7674_RS08585 (SPNIH35_16460)	-	1766441..1766641 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
H7674_RS08590 (SPNIH35_16470)	-	1766662..1767069 (+)	408	WP_002992501.1	hypothetical protein	-
H7674_RS09240 (SPNIH35_16480)	-	1767082..1767204 (+)	123	WP_011285272.1	hypothetical protein	-
H7674_RS08595 (SPNIH35_16490)	-	1767487..1768008 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
H7674_RS08600 (SPNIH35_16500)	-	1768256..1768429 (+)	174	WP_000132665.1	hypothetical protein	-
H7674_RS08605 (SPNIH35_16510)	-	1768647..1768820 (+)	174	WP_000074663.1	plasmid mobilization protein	-
H7674_RS08610 (SPNIH35_16520)	-	1768982..1769413 (+)	432	WP_136302445.1	hypothetical protein	-
H7674_RS08615 (SPNIH35_16530)	-	1769515..1769847 (+)	333	WP_011285276.1	hypothetical protein	-
H7674_RS08620 (SPNIH35_16540)	-	1769847..1770038 (+)	192	WP_021340709.1	hypothetical protein	-
H7674_RS08625 (SPNIH35_16550)	-	1770050..1770379 (+)	330	WP_003058810.1	hypothetical protein	-
H7674_RS08630 (SPNIH35_16560)	-	1770382..1770654 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=70409 H7674_RS08575 WP_003058809.1 1765280..1766047(-) (irvR) [Streptococcus pyogenes strain NIH35]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=70409 H7674_RS08575 WP_003058809.1 1765280..1766047(-) (irvR) [Streptococcus pyogenes strain NIH35]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4