Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   KUN2590_RS03635 Genome accession   NZ_AP023387
Coordinates   672139..672321 (+) Length   60 a.a.
NCBI ID   WP_011054726.1    Uniprot ID   A0A0H2UVL5
Organism   Streptococcus pyogenes strain NIH34     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context


Location: 667139..677321
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KUN2590_RS03615 (SPNIH34_06580) - 668281..668805 (+) 525 WP_011017840.1 Panacea domain-containing protein -
  KUN2590_RS03620 (SPNIH34_06590) - 668793..669659 (+) 867 WP_011054729.1 DUF334 domain-containing protein -
  KUN2590_RS03625 (SPNIH34_06600) spek 669963..670742 (+) 780 WP_011054728.1 streptococcal pyrogenic exotoxin SpeK -
  KUN2590_RS03630 (SPNIH34_06610) - 671218..671793 (+) 576 WP_011054727.1 hypothetical protein -
  KUN2590_RS03635 (SPNIH34_06620) prx 672139..672321 (+) 183 WP_011054726.1 hypothetical protein Regulator
  KUN2590_RS03640 (SPNIH34_06630) - 672566..673306 (+) 741 WP_011054725.1 response regulator -
  KUN2590_RS03645 (SPNIH34_06640) - 673303..675036 (+) 1734 WP_011054724.1 sensor histidine kinase -
  KUN2590_RS03650 (SPNIH34_06650) - 675109..676188 (+) 1080 WP_011054723.1 MmcQ/YjbR family DNA-binding protein -
  KUN2590_RS03655 (SPNIH34_06660) - 676202..676918 (+) 717 WP_011054722.1 B3/4 domain-containing protein -

Sequence


Protein


Download         Length: 60 a.a.        Molecular weight: 6771.70 Da        Isoelectric Point: 3.9944

>NTDB_id=70265 KUN2590_RS03635 WP_011054726.1 672139..672321(+) (prx) [Streptococcus pyogenes strain NIH34]
MLTYDEFKQAIDNGYIVGDTVAIVRKNGQIFDYVLPGEKVRPSEVVAEEIVEEVVVELDK

Nucleotide


Download         Length: 183 bp        

>NTDB_id=70265 KUN2590_RS03635 WP_011054726.1 672139..672321(+) (prx) [Streptococcus pyogenes strain NIH34]
ATGCTAACATACGACGAGTTTAAGCAAGCGATTGACAATGGATATATCGTAGGAGACACAGTAGCGATTGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCTGGCGAAAAAGTCAGACCGTCGGAGGTTGTGGCTGAGGAAATAGTGGAAGAGG
TGGTGGTGGAATTAGACAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A0H2UVL5

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

100

1

  prx Streptococcus pyogenes MGAS8232

80

100

0.8

  prx Streptococcus pyogenes MGAS315

80

100

0.8

  prx Streptococcus pyogenes MGAS315

80

100

0.8

  prx Streptococcus pyogenes MGAS315

78.333

100

0.783

  prx Streptococcus pyogenes MGAS315

73.333

100

0.733

  prx Streptococcus pyogenes MGAS315

87.805

68.333

0.6


Multiple sequence alignment