Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   NEE09_RS08565 Genome accession   NZ_CP099641
Coordinates   1644433..1646076 (+) Length   547 a.a.
NCBI ID   WP_078133841.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ATCC 700671     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1639433..1651076
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NEE09_RS08515 blpN 1639796..1639999 (-) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  NEE09_RS08520 blpM 1640015..1640269 (-) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  NEE09_RS08525 - 1640419..1641223 (-) 805 Protein_1634 IS5 family transposase -
  NEE09_RS08530 - 1641421..1641825 (-) 405 WP_000846944.1 hypothetical protein -
  NEE09_RS08535 - 1641822..1641986 (-) 165 WP_000727118.1 hypothetical protein -
  NEE09_RS08540 - 1642283..1642402 (-) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  NEE09_RS08545 blpU 1642405..1642635 (-) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  NEE09_RS08550 blpJ 1642704..1642973 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  NEE09_RS08555 blpI 1643440..1643637 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  NEE09_RS08560 comA/nlmT 1643919..1644506 (+) 588 WP_001810228.1 cysteine peptidase family C39 domain-containing protein Regulator
  NEE09_RS08565 comA/nlmT 1644433..1646076 (+) 1644 WP_078133841.1 peptide cleavage/export ABC transporter Regulator
  NEE09_RS08570 - 1646087..1647448 (+) 1362 WP_001069091.1 bacteriocin secretion accessory protein -
  NEE09_RS08575 blpC 1647505..1647660 (+) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  NEE09_RS08580 - 1647702..1649042 (-) 1341 WP_001017638.1 sensor histidine kinase -
  NEE09_RS08585 comE/blpR 1649056..1649793 (-) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  NEE09_RS08590 - 1649798..1650136 (-) 339 WP_000682135.1 LytTR family DNA-binding domain-containing protein -
  NEE09_RS08595 - 1650413..1650742 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61617.57 Da        Isoelectric Point: 6.5088

>NTDB_id=701221 NEE09_RS08565 WP_078133841.1 1644433..1646076(+) (comA/nlmT) [Streptococcus pneumoniae strain ATCC 700671]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKSPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=701221 NEE09_RS08565 WP_078133841.1 1644433..1646076(+) (comA/nlmT) [Streptococcus pneumoniae strain ATCC 700671]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTAGATGAATACAT
CCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGAGTCTTGCTGGCACAAA
ACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATTTCCATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTATATCTTT
AATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGATTAGTCAAGAAGATATTCTAAAAGCTTGTGAAGT
AGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGATGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGCCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(2-268)

ABC transporter (ABC_tran)

(330-479)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.894

99.817

0.728
  comA Streptococcus mitis NCTC 12261

67.459

100

0.675
  comA Streptococcus pneumoniae D39

67.093

100

0.671
  comA Streptococcus pneumoniae R6

67.093

100

0.671
  comA Streptococcus pneumoniae Rx1

67.093

100

0.671
  comA Streptococcus gordonii str. Challis substr. CH1

66.788

100

0.669
  comA Streptococcus mitis SK321

66.91

100

0.669
  comA Streptococcus pneumoniae TIGR4

66.728

100

0.667