Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SA27298_RS04780 Genome accession   NZ_AP018548
Coordinates   982540..983244 (-) Length   234 a.a.
NCBI ID   WP_003031685.1    Uniprot ID   A0A448AGW3
Organism   Streptococcus anginosus strain CCUG 27928     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 977540..988244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA27298_RS04765 (SA27298_0973) - 978062..979048 (-) 987 WP_003024723.1 Gfo/Idh/MocA family oxidoreductase -
  SA27298_RS04770 (SA27298_0975) - 979679..980245 (-) 567 WP_223349562.1 DUF805 domain-containing protein -
  SA27298_RS04775 (SA27298_0976) comEC/celB 980328..982556 (-) 2229 WP_003031687.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SA27298_RS04780 (SA27298_0977) comEA/celA/cilE 982540..983244 (-) 705 WP_003031685.1 helix-hairpin-helix domain-containing protein Machinery gene
  SA27298_RS04785 (SA27298_0979) smpB 983425..983892 (-) 468 WP_003031704.1 SsrA-binding protein SmpB -
  SA27298_RS04790 (SA27298_0980) rnr 983855..986188 (-) 2334 WP_018543505.1 ribonuclease R -
  SA27298_RS04795 (SA27298_0981) secG 986280..986513 (-) 234 WP_003024744.1 preprotein translocase subunit SecG -
  SA27298_RS04800 rpmG 986553..986702 (-) 150 WP_003024746.1 50S ribosomal protein L33 -
  SA27298_RS04805 (SA27298_0982) - 986686..987891 (-) 1206 WP_003032823.1 multidrug efflux MFS transporter -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 25081.12 Da        Isoelectric Point: 4.7769

>NTDB_id=69984 SA27298_RS04780 WP_003031685.1 982540..983244(-) (comEA/celA/cilE) [Streptococcus anginosus strain CCUG 27928]
MLETIIEKMKEYKILIGLSLIGLIIAGFFMINGQSSRRSNVAELAQETVTSSEAELEEISTGTKKNSQKEKAEPQTSSSE
ESEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLMTDADSKSINLAQKLTDEAVVYVATMGENAASVSSNTGQSSTS
GTSEVASQKGNKVNLNTADLSELQTISGIGQKRAQDILDYREANGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=69984 SA27298_RS04780 WP_003031685.1 982540..983244(-) (comEA/celA/cilE) [Streptococcus anginosus strain CCUG 27928]
ATGTTAGAGACAATCATTGAAAAGATGAAAGAGTATAAAATTTTGATTGGTTTAAGTTTGATTGGTTTGATAATAGCAGG
ATTTTTTATGATAAATGGTCAATCTAGTAGACGATCAAATGTAGCAGAGCTCGCACAGGAAACAGTTACGAGTTCGGAGG
CAGAATTAGAAGAAATTTCAACTGGAACGAAGAAAAACTCACAGAAAGAAAAAGCAGAGCCTCAAACGAGTTCCAGTGAA
GAATCAGAATTTTTAACCGTAGATGTCAAGGGTGCAGTCAAAAATCCAGGTATTTATCAACTGAAAAAGACTAGCCGTAT
CAATGATGCGATTCAAAAAGCAGGTGGTTTAATGACAGACGCTGACAGCAAGTCTATCAATTTGGCGCAGAAACTAACGG
ATGAAGCTGTTGTTTATGTGGCAACTATGGGTGAGAATGCGGCGAGTGTTTCAAGCAATACAGGACAATCTTCAACGTCA
GGAACTAGTGAAGTCGCATCGCAAAAAGGGAATAAGGTCAATCTAAATACAGCTGATTTATCTGAGTTGCAGACCATTTC
TGGTATTGGTCAAAAACGCGCGCAAGATATTTTAGATTATCGGGAGGCAAACGGGAAATTTAATTCCGTTGATGACCTGA
AAAATGTATCAGGAGTAGGTGCTAAAACACTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A448AGW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae Rx1

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae D39

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus pneumoniae R6

52.361

99.573

0.521
  comEA/celA/cilE Streptococcus mitis SK321

51.931

99.573

0.517
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.073

99.573

0.509
  comEA Streptococcus thermophilus LMD-9

43.404

100

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

41.202

99.573

0.41

Multiple sequence alignment