Detailed information NTG0695407

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: NCL52_RS17360
• Genome accession: NZ_CP098417
• Coordinates: 3375697..3376290 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain N2-10
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3370697..3381290

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NCL52_RS17325 (NCL52_17325)	-	3371683..3372267 (+)	585	WP_175405003.1	TetR family transcriptional regulator	-
NCL52_RS17330 (NCL52_17330)	psmA	3372349..3372684 (+)	336	WP_014480966.1	SMR family transporter	-
NCL52_RS17335 (NCL52_17335)	psmB	3372684..3373004 (+)	321	WP_021480661.1	QacE family quaternary ammonium compound efflux SMR transporter	-
NCL52_RS17340 (NCL52_17340)	yvdQ	3373040..3373552 (-)	513	WP_134982547.1	DUF3231 family protein	-
NCL52_RS20790	-	3373572..3373841 (-)	270	WP_137201035.1	poly-gamma-glutamate hydrolase family protein	-
NCL52_RS17350 (NCL52_17350)	cotR	3374031..3374993 (+)	963	WP_024573362.1	sporulation hydrolase CotR	-
NCL52_RS17360 (NCL52_17360)	clpP	3375697..3376290 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
NCL52_RS17365 (NCL52_17365)	pgmB	3376353..3377027 (-)	675	WP_137201037.1	beta-phosphoglucomutase	-
NCL52_RS17370 (NCL52_17370)	malL	3377024..3378709 (-)	1686	WP_086344354.1	oligo-1,6-glucosidase	-
NCL52_RS17375 (NCL52_17375)	mdxK	3378702..3380975 (-)	2274	WP_086344355.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=695407 NCL52_RS17360 WP_003228214.1 3375697..3376290(+) (clpP) [Bacillus subtilis strain N2-10]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=695407 NCL52_RS17360 WP_003228214.1 3375697..3376290(+) (clpP) [Bacillus subtilis strain N2-10]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGAGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGATAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538