Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   SR187_RS04515 Genome accession   NZ_AP018400
Coordinates   927929..928771 (+) Length   280 a.a.
NCBI ID   WP_024532815.1    Uniprot ID   -
Organism   Streptococcus ruminantium strain GUT-187     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 922929..933771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SR187_RS04485 (SR187_4590) ylqF 923089..923940 (+) 852 WP_120171644.1 ribosome biogenesis GTPase YlqF -
  SR187_RS04490 (SR187_4595) - 923927..924703 (+) 777 WP_120171645.1 ribonuclease HII -
  SR187_RS04495 (SR187_4600) - 924703..925713 (+) 1011 WP_024532811.1 YdcF family protein -
  SR187_RS04500 (SR187_4605) - 925893..926543 (-) 651 WP_024532812.1 hemolysin III family protein -
  SR187_RS04505 (SR187_4610) - 926533..926979 (-) 447 WP_024532813.1 DUF1836 domain-containing protein -
  SR187_RS04510 (SR187_4615) - 927311..927868 (+) 558 WP_120171646.1 sugar O-acetyltransferase -
  SR187_RS04515 (SR187_4620) dprA 927929..928771 (+) 843 WP_024532815.1 DNA-processing protein DprA Machinery gene
  SR187_RS04520 (SR187_4625) topA 928865..930958 (+) 2094 WP_024532816.1 type I DNA topoisomerase -
  SR187_RS04525 (SR187_4630) rplJ 931345..931839 (+) 495 WP_024532817.1 50S ribosomal protein L10 -
  SR187_RS04530 (SR187_4635) rplL 931906..932271 (+) 366 WP_024532818.1 50S ribosomal protein L7/L12 -
  SR187_RS09940 (SR187_4640) - 932531..932704 (+) 174 WP_120172473.1 hypothetical protein -
  SR187_RS04540 (SR187_4645) - 932701..933525 (+) 825 Protein_836 replication initiator protein A -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31195.25 Da        Isoelectric Point: 9.0392

>NTDB_id=69453 SR187_RS04515 WP_024532815.1 927929..928771(+) (dprA) [Streptococcus ruminantium strain GUT-187]
MNNFELFKLKKAGLTNLNINKVLAYREKYGKQLSIRNIAVVSECKNPILFMENYKSLDLKACRQEFNKYPSLSILDDSYP
LALKQIYNPPVLLFYQGDLELLDKPKLAVVGTRTASKNGIQSVRKILKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVVGAGLDIVYPKENKELQHYIGKNHLLLTEYEPSAKPLKFHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSILDGKSDGCHHLIQEGAKCITSGLDIISDYQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=69453 SR187_RS04515 WP_024532815.1 927929..928771(+) (dprA) [Streptococcus ruminantium strain GUT-187]
ATGAATAACTTTGAACTATTTAAACTAAAAAAAGCTGGACTAACTAATCTCAACATCAACAAGGTCTTGGCTTATAGAGA
AAAATATGGTAAACAATTGTCCATTCGGAATATTGCTGTTGTCTCAGAGTGCAAGAATCCAATTCTTTTTATGGAAAATT
ATAAGAGTTTAGATTTAAAAGCTTGCAGACAAGAGTTTAATAAGTACCCATCCCTATCCATTTTAGACGATAGCTATCCC
TTGGCATTAAAACAGATTTATAATCCACCCGTCCTCTTATTTTATCAAGGTGATTTGGAACTCTTAGACAAGCCCAAGCT
AGCTGTGGTAGGGACACGAACTGCCAGTAAAAATGGTATCCAATCCGTCCGAAAGATTCTAAAAGAACTCAACAATCGCT
TTGTTATTGTTAGCGGTCTAGCGAGAGGAATTGACACAGCAGCTCATATTGCCAGCCTAAAGAATGGCGGACAAACGATT
GCTGTTGTTGGAGCTGGCTTGGATATAGTCTACCCAAAGGAAAATAAGGAACTACAACACTATATTGGAAAGAATCATTT
ACTCCTAACAGAGTACGAACCGAGTGCCAAACCTCTCAAATTTCATTTTCCAGAGCGCAATCGTATTATTGCTGGTTTGG
TTGAAGGTTTGGTAGTTTGCGAAGCCAAAATGCGGTCTGGTAGTTTGATTACCTGTGAAAGAGCTTTGGAGGAAGGTAGA
GAAGTTTATGCCATTCCAGGATCTATTTTAGATGGAAAATCAGATGGTTGTCACCATTTGATACAGGAAGGTGCCAAATG
TATTACAAGTGGTTTGGATATCATTTCAGATTATCAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

69.286

100

0.693
  dprA/cilB/dalA Streptococcus mitis SK321

62.5

100

0.625
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

62.5

100

0.625
  dprA/cilB/dalA Streptococcus pneumoniae D39

62.5

100

0.625
  dprA/cilB/dalA Streptococcus pneumoniae R6

62.5

100

0.625
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

62.5

100

0.625
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

61.786

100

0.618
  dprA Lactococcus lactis subsp. cremoris KW2

57.143

100

0.571
  dprA Latilactobacillus sakei subsp. sakei 23K

44.017

83.571

0.368
  dprA Legionella pneumophila strain ERS1305867

41.296

88.214

0.364
  dprA Bacillus subtilis subsp. subtilis str. 168

48.804

74.643

0.364

Multiple sequence alignment