Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   SR187_RS00810 Genome accession   NZ_AP018400
Coordinates   126103..126396 (+) Length   97 a.a.
NCBI ID   WP_120172446.1    Uniprot ID   A0A2Z5U255
Organism   Streptococcus ruminantium strain GUT-187     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 121103..131396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SR187_RS00780 (SR187_0805) - 122033..122401 (+) 369 WP_120171203.1 DUF1033 family protein -
  SR187_RS00785 (SR187_0810) - 122439..123389 (-) 951 WP_024532257.1 S66 peptidase family protein -
  SR187_RS00790 (SR187_0815) comYA 123551..124501 (+) 951 WP_120171204.1 competence type IV pilus ATPase ComGA Machinery gene
  SR187_RS00795 (SR187_0820) comYB 124422..125453 (+) 1032 WP_120171205.1 competence type IV pilus assembly protein ComGB Machinery gene
  SR187_RS00800 (SR187_0825) comYC 125450..125731 (+) 282 WP_024532254.1 competence type IV pilus major pilin ComGC Machinery gene
  SR187_RS00805 (SR187_0830) comGD 125718..126131 (+) 414 WP_024532253.1 competence type IV pilus minor pilin ComGD -
  SR187_RS00810 (SR187_0835) comYE 126103..126396 (+) 294 WP_120172446.1 competence type IV pilus minor pilin ComGE Machinery gene
  SR187_RS00815 (SR187_0840) comGF/cglF 126383..126817 (+) 435 WP_120171206.1 competence type IV pilus minor pilin ComGF Machinery gene
  SR187_RS00820 (SR187_0845) comGG 126795..127208 (+) 414 WP_120171207.1 competence type IV pilus minor pilin ComGG -
  SR187_RS00825 (SR187_0850) comYH 127213..128166 (+) 954 WP_120171208.1 class I SAM-dependent methyltransferase Machinery gene
  SR187_RS00830 (SR187_0855) - 128216..129403 (+) 1188 WP_120171209.1 acetate kinase -
  SR187_RS00835 (SR187_0860) - 129708..130262 (+) 555 WP_120171210.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10868.84 Da        Isoelectric Point: 10.4805

>NTDB_id=69430 SR187_RS00810 WP_120172446.1 126103..126396(+) (comYE) [Streptococcus ruminantium strain GUT-187]
MVVIKNQKNKAYVLLESLVALAVFVAICSLLLSAITAGRRRQAWELKQQEILNLAQMAVQTKQHHLVLNGVEVTVQRSSN
QLVVFHEGKEVLHIAKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=69430 SR187_RS00810 WP_120172446.1 126103..126396(+) (comYE) [Streptococcus ruminantium strain GUT-187]
GTGGTCGTTATAAAAAATCAGAAGAATAAGGCCTATGTTTTGCTAGAAAGTTTGGTAGCATTGGCGGTCTTTGTTGCTAT
TTGTAGCTTGCTTCTATCAGCTATAACTGCTGGCCGGAGGCGTCAGGCTTGGGAATTAAAACAACAGGAAATTCTCAATC
TGGCTCAGATGGCTGTGCAGACCAAGCAACATCATTTGGTACTCAATGGTGTGGAGGTGACTGTACAACGGAGTTCAAAT
CAATTAGTCGTTTTTCACGAAGGGAAGGAGGTTTTGCACATTGCTAAAAACTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5U255

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

52.083

98.969

0.515
  comYE Streptococcus mutans UA159

52.083

98.969

0.515
  comGE/cglE Streptococcus mitis SK321

42.857

93.814

0.402
  comGE/cglE Streptococcus mitis NCTC 12261

42.857

93.814

0.402
  comGE/cglE Streptococcus pneumoniae D39

41.758

93.814

0.392
  comGE/cglE Streptococcus pneumoniae Rx1

41.758

93.814

0.392
  comGE/cglE Streptococcus pneumoniae R6

41.758

93.814

0.392
  comGE/cglE Streptococcus pneumoniae TIGR4

41.758

93.814

0.392
  comGE Lactococcus lactis subsp. cremoris KW2

37.234

96.907

0.361

Multiple sequence alignment