Detailed information NTG0069418

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: SR187_RS00350
• Genome accession: NZ_AP018400
• Coordinates: 53495..55648 (+)
• Length: 717 a.a.
• NCBI ID: WP_120171173.1
• Uniprot ID: -
• Organism: Streptococcus ruminantium strain GUT-187
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 48495..60648

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SR187_RS00315 (SR187_0310)	purB	49068..50360 (+)	1293	WP_120171167.1	adenylosuccinate lyase	-
SR187_RS09875 (SR187_0315)	-	50678..50821 (+)	144	WP_155962526.1	hypothetical protein	-
SR187_RS00320 (SR187_0320)	-	50874..51062 (+)	189	WP_024533071.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SR187_RS00325 (SR187_0330)	-	51272..51454 (+)	183	WP_024533150.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SR187_RS00330 (SR187_0335)	-	51538..51726 (+)	189	WP_120171169.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SR187_RS00335 (SR187_0345)	-	51936..52130 (+)	195	WP_024533168.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SR187_RS00340 (SR187_0350)	-	52336..52491 (+)	156	WP_024533167.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SR187_RS00345 (SR187_0355)	-	52546..52737 (+)	192	WP_120171171.1	hypothetical protein	-
SR187_RS09880 (SR187_0365)	-	53003..53149 (+)	147	WP_155962530.1	hypothetical protein	-
SR187_RS00350 (SR187_0370)	comA	53495..55648 (+)	2154	WP_120171173.1	peptide cleavage/export ABC transporter ComA	Regulator
SR187_RS00355 (SR187_0375)	comB	55654..57024 (+)	1371	WP_323131747.1	bacteriocin secretion accessory protein	Regulator
SR187_RS00360 (SR187_0380)	ruvB	57453..58451 (+)	999	WP_024532316.1	Holliday junction branch migration DNA helicase RuvB	-
SR187_RS00365 (SR187_0385)	-	58623..59246 (+)	624	WP_120172445.1	HAD-IA family hydrolase	-
SR187_RS00370 (SR187_0390)	comR	59349..60251 (+)	903	WP_120171177.1	helix-turn-helix domain-containing protein	Regulator

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80966.11 Da
• Isoelectric Point: 7.0769

>NTDB_id=69418 SR187_RS00350 WP_120171173.1 53495..55648(+) (comA) [Streptococcus ruminantium strain GUT-187]
MKFRKRHYRAQVDTRDCGVAALAMILEYHHSHHSLASLRELAKTTMEGTTAFGLVKVAEDLGLETRAIRADMSLFEVGDL
TYPFIAHVLKDGKLMHYYVVTGADEKTIHIADPDPSVKLTKLTRERFEQEWTGVSLFMAPRPEYQPHKEKKQGLLSFVPL
LAKQKRLIGNIILATLLVTLINIVGSYYLQSIIDTYVPNQMKTTLGVISIGLVVVYALQQLLSYAQEYLLIILGQRLSID
VILSYIRHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSIILIISVVLFSQNIYLFFIALLSLPIYSV
IIFAFMKPFERMNQEVMETNAVLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVDYLKKSFAYNKAEGQQKVLKRLAQL
VLNVAILWLGATLVMDNKMTLGQLITFNTLLVYFTNPLENIINLQTKLQTARVANNRLNEVYLVESEFADQKTVTDLSLV
SGDIDFRDVSYKYGYGADVLSDINLTIKRGEKISFVGVSGSGKTTLAKMMVNFYDPYKGEINLNNVNLNQIDKHALRQHI
NYLPQQPYIFNGTILENLLLGAKEGTTQEDVLRAVEIACIREDIEKMPLNYQTELTSDGSGISGGQRQRIALARALLTDA
PIMILDEATSSLDILTEKRIVDNLLALDKTLIFIVHRLTIAERTERVVVLDKGKIVEQGCHRELLDQQGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=69418 SR187_RS00350 WP_120171173.1 53495..55648(+) (comA) [Streptococcus ruminantium strain GUT-187]
ATGAAGTTTAGGAAACGGCATTATAGGGCTCAGGTGGATACACGAGATTGTGGTGTAGCCGCTCTTGCAATGATTTTGGA
GTACCATCATTCTCATCATTCTTTGGCAAGTCTTCGAGAACTGGCTAAAACAACCATGGAAGGAACGACAGCTTTTGGAC
TAGTTAAAGTAGCCGAAGACTTGGGGCTTGAAACTCGCGCAATTCGAGCAGATATGTCCTTATTTGAGGTGGGAGATTTA
ACTTATCCCTTCATAGCTCATGTACTGAAAGATGGCAAGCTCATGCACTACTACGTTGTTACGGGTGCGGATGAGAAGAC
CATCCATATTGCAGATCCCGATCCTTCGGTCAAGTTAACCAAGTTAACTCGTGAACGATTTGAACAGGAATGGACAGGGG
TATCCTTATTCATGGCTCCTAGACCGGAATATCAACCTCACAAAGAGAAGAAGCAAGGCTTGTTGTCTTTTGTTCCCTTG
CTGGCAAAGCAAAAGAGATTGATTGGCAATATTATTTTGGCTACTCTTTTGGTGACGCTCATCAATATTGTTGGATCTTA
TTATCTACAATCCATCATTGATACCTATGTTCCAAATCAGATGAAGACAACTTTGGGAGTTATCTCAATTGGTTTAGTTG
TGGTGTATGCCTTGCAACAGTTGTTGTCTTACGCACAAGAGTATCTGCTCATTATACTAGGGCAAAGACTATCTATAGAT
GTTATCCTATCTTATATCAGACATGTATTCCATTTGCCAATGTCTTTTTTTGCAACACGGCGCACAGGGGAAATCGTTTC
TCGCTTTACAGATGCAAACTCTATTATTGATGCTTTGGCAAGTACAATTCTATCTATTTTCTTAGATGTATCCATTATTT
TGATTATTTCGGTTGTCTTATTTAGTCAGAACATTTACTTGTTTTTTATAGCTTTGTTGTCATTGCCGATTTATTCTGTC
ATTATTTTTGCATTTATGAAGCCATTTGAACGCATGAATCAGGAAGTAATGGAAACAAATGCTGTTTTGTCTTCTTCTAT
TATTGAAGACATCAATGGCATTGAAACAATTAAATCATTGACCAGTGAAAAACAACGTTATCAGAAAATTGATAAAGAAT
TTGTAGACTATCTGAAAAAATCTTTTGCCTATAACAAGGCAGAAGGACAACAAAAAGTGTTAAAGCGCTTGGCTCAGCTA
GTGCTGAACGTGGCTATTTTGTGGTTGGGAGCAACTCTCGTCATGGACAATAAGATGACGCTCGGTCAGCTCATCACGTT
CAATACCTTATTGGTCTACTTCACTAATCCTCTGGAAAATATTATCAATCTACAAACAAAACTTCAAACAGCTCGTGTAG
CAAATAATCGTCTCAATGAAGTTTATTTAGTTGAATCTGAGTTTGCGGATCAAAAGACAGTCACTGACTTGTCCCTGGTT
TCAGGAGATATTGATTTTAGAGATGTTAGTTATAAATATGGGTATGGTGCAGATGTCTTGTCAGACATCAATTTGACAAT
CAAGCGTGGTGAGAAGATTTCTTTTGTCGGAGTTTCTGGATCAGGTAAAACAACGCTGGCCAAGATGATGGTAAATTTTT
ATGATCCTTATAAGGGGGAGATTAACTTGAACAATGTAAATCTCAACCAAATTGACAAGCATGCTTTGCGTCAGCACATC
AATTACTTACCACAACAACCCTATATTTTTAATGGAACTATTTTAGAGAATCTCTTGCTAGGTGCCAAAGAGGGAACCAC
TCAGGAGGATGTCTTGCGAGCAGTAGAAATTGCCTGTATCAGAGAAGACATTGAAAAAATGCCTCTGAATTATCAGACGG
AGCTGACATCGGATGGATCAGGTATATCGGGTGGTCAACGCCAGCGCATCGCTCTGGCTCGAGCGTTGTTGACAGATGCT
CCGATTATGATTTTGGATGAGGCTACCAGTAGTTTAGACATCCTGACGGAGAAGCGAATTGTTGATAATTTGCTCGCCTT
GGATAAGACATTGATTTTTATTGTTCATCGTCTAACCATTGCGGAACGAACAGAGCGTGTCGTTGTACTTGATAAGGGAA
AAATTGTGGAACAAGGTTGCCATAGAGAACTACTCGATCAACAGGGATTTTATGCACATTTAGTAAATAGTTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	81.172	100	0.812
comA	Streptococcus pneumoniae Rx1	81.032	100	0.81
comA	Streptococcus pneumoniae D39	81.032	100	0.81
comA	Streptococcus pneumoniae R6	81.032	100	0.81
comA	Streptococcus mitis SK321	80.893	100	0.809
comA	Streptococcus pneumoniae TIGR4	80.753	100	0.808
comA	Streptococcus gordonii str. Challis substr. CH1	78.103	100	0.781
comA/nlmT	Streptococcus mutans UA159	63.877	100	0.639