Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SR187_RS00370 Genome accession   NZ_AP018400
Coordinates   59349..60251 (+) Length   300 a.a.
NCBI ID   WP_120171177.1    Uniprot ID   A0A2Z5TMK0
Organism   Streptococcus ruminantium strain GUT-187     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 54349..65251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SR187_RS00355 (SR187_0375) comB 55654..57024 (+) 1371 WP_323131747.1 bacteriocin secretion accessory protein Regulator
  SR187_RS00360 (SR187_0380) ruvB 57453..58451 (+) 999 WP_024532316.1 Holliday junction branch migration DNA helicase RuvB -
  SR187_RS00365 (SR187_0385) - 58623..59246 (+) 624 WP_120172445.1 HAD-IA family hydrolase -
  SR187_RS00370 (SR187_0390) comR 59349..60251 (+) 903 WP_120171177.1 helix-turn-helix domain-containing protein Regulator
  SR187_RS00375 (SR187_0395) - 60453..61682 (+) 1230 WP_120171179.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  SR187_RS00385 (SR187_0405) - 61884..63383 (+) 1500 WP_120171182.1 quinol oxidase -

Sequence

Protein


Download         Length: 300 a.a.        Molecular weight: 35633.78 Da        Isoelectric Point: 4.6520

>NTDB_id=69420 SR187_RS00370 WP_120171177.1 59349..60251(+) (comR) [Streptococcus ruminantium strain GUT-187]
MDNKEFGQRVRQLREQAMITREQFCDDEIELSVRQLTRIEAGTCKPTFSKINFIADRLGMGLYELMPDYIKLPERYSKLK
FDVLRTPTYGNEGLVETRNEMITEIYEEYYDDLPEEEQIAMDAFQSRLDTLESGVEGFGKEILEDYFEQVFRKPKYEVND
LLIIRLHLEYVRLADRNSEIFLHFLGLIEELHKQIDVVSAGDLFVLRDTLLSCVNILGSKKYYEPILKIFDSVDKITQLT
QDFQKKPIISLMKWKYALFVTKDRKEAERHYQEAKLFSQLIENEILKQKIDEEWKTDTQQ

Nucleotide


Download         Length: 903 bp        

>NTDB_id=69420 SR187_RS00370 WP_120171177.1 59349..60251(+) (comR) [Streptococcus ruminantium strain GUT-187]
ATGGATAATAAGGAATTTGGTCAGCGTGTACGGCAACTACGAGAACAAGCAATGATAACACGAGAACAGTTTTGTGATGA
TGAAATAGAACTCTCTGTTCGTCAGTTAACTCGGATTGAGGCTGGTACCTGTAAACCAACATTTTCTAAGATAAATTTTA
TCGCCGATCGTTTGGGGATGGGTCTATATGAACTAATGCCAGATTACATCAAACTACCAGAGAGATATTCAAAATTGAAA
TTTGATGTTCTGCGAACGCCTACATATGGGAATGAGGGATTGGTAGAAACACGTAACGAAATGATCACGGAAATTTATGA
AGAGTATTATGATGACTTGCCAGAAGAAGAACAAATAGCAATGGATGCTTTTCAATCGCGTCTTGACACACTGGAATCAG
GTGTTGAGGGATTTGGTAAAGAAATATTAGAAGACTATTTTGAACAAGTGTTTCGTAAACCTAAGTATGAAGTAAATGAT
TTATTAATTATTCGACTTCATCTTGAATACGTACGACTTGCGGATCGTAACTCGGAGATATTTCTTCATTTTCTGGGTCT
CATTGAAGAGTTACATAAACAGATTGATGTAGTTAGTGCAGGTGATCTGTTCGTTTTGCGTGATACATTACTATCTTGTG
TGAACATATTGGGTAGCAAAAAATATTATGAACCTATTCTAAAGATATTCGATAGTGTGGATAAAATTACACAGTTAACA
CAGGATTTTCAAAAAAAGCCCATTATTAGCTTGATGAAATGGAAATATGCTCTTTTTGTTACAAAAGATAGAAAAGAAGC
TGAGCGGCATTATCAAGAAGCGAAATTATTTTCCCAGTTAATAGAAAATGAGATTTTAAAGCAGAAAATTGATGAGGAAT
GGAAAACTGATACCCAACAATAG

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TMK0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

76.589

99.667

0.763
  comR Streptococcus suis 05ZYH33

76.589

99.667

0.763
  comR Streptococcus suis D9

56.478

100

0.567
  comR Streptococcus mutans UA159

43

100

0.43
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

39.931

96

0.383
  comR Streptococcus pyogenes MGAS315

37.584

99.333

0.373

Multiple sequence alignment