Detailed information NTG0692937

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: M9H69_RS06975
• Genome accession: NZ_CP097843
• Coordinates: 1352487..1353077 (-)
• Length: 196 a.a.
• NCBI ID: WP_000613469.1
• Uniprot ID: A0A0F2E4Z4
• Organism: Streptococcus oralis strain HP01
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1347487..1358077

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H69_RS06950 (M9H69_06950)	-	1348177..1348941 (-)	765	WP_001186017.1	ABC transporter ATP-binding protein	-
M9H69_RS06955 (M9H69_06955)	-	1348941..1349897 (-)	957	WP_250315198.1	branched-chain amino acid ABC transporter permease	-
M9H69_RS06960 (M9H69_06960)	-	1349901..1350770 (-)	870	WP_000941407.1	branched-chain amino acid ABC transporter permease	-
M9H69_RS06965 (M9H69_06965)	-	1350891..1352051 (-)	1161	WP_250315199.1	ABC transporter substrate-binding protein	-
M9H69_RS06970 (M9H69_06970)	-	1352139..1352408 (-)	270	WP_061597844.1	YlbG family protein	-
M9H69_RS06975 (M9H69_06975)	clpP	1352487..1353077 (-)	591	WP_000613469.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
M9H69_RS06980 (M9H69_06980)	upp	1353251..1353880 (-)	630	WP_000515972.1	uracil phosphoribosyltransferase	-
M9H69_RS06985 (M9H69_06985)	-	1353969..1354436 (-)	468	WP_000136990.1	cytidine/deoxycytidylate deaminase family protein	-
M9H69_RS06990 (M9H69_06990)	-	1354448..1355011 (-)	564	WP_250315200.1	TetR/AcrR family transcriptional regulator	-
M9H69_RS06995 (M9H69_06995)	-	1355136..1355981 (+)	846	WP_061597848.1	DegV family protein	-
M9H69_RS07000 (M9H69_07000)	-	1356039..1357214 (+)	1176	WP_250315201.1	NAD(P)/FAD-dependent oxidoreductase	-
M9H69_RS07005 (M9H69_07005)	-	1357234..1357689 (+)	456	WP_250315202.1	8-oxo-dGTP diphosphatase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21404.45 Da
• Isoelectric Point: 4.4829

>NTDB_id=692937 M9H69_RS06975 WP_000613469.1 1352487..1353077(-) (clpP) [Streptococcus oralis strain HP01]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILADNSGK
TVEQIHVDAERDYWMSAQETLEYGFIDEIMANNSLS

Nucleotide

• Length: 591 bp

>NTDB_id=692937 M9H69_RS06975 WP_000613469.1 1352487..1353077(-) (clpP) [Streptococcus oralis strain HP01]
ATGATTCCTGTAGTTATTGAACAAACAAGTCGTGGAGAACGTTCATATGATATTTACTCACGTCTACTAAAAGATCGTAT
CATCATGTTGACTGGACCAGTTGAAGACAACATGGCCAACTCCGTTATTGCTCAATTGCTCTTCTTGGATGCTCAAGATA
GTACAAAAGATATTTACCTTTATGTAAATACTCCGGGTGGTTCTGTATCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACAATCGTTATGGGGATGGCTGCATCCATGGGAACTGTCATTGCATCAAGTGGCGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAGA
CAGATATGGCAATCGCTGCAGAGCACTTACTTAAAACTCGTAAGACTTTGGAGCAGATTCTTGCAGATAACTCTGGTAAA
ACAGTTGAGCAAATTCATGTAGACGCAGAACGTGATTACTGGATGAGTGCCCAAGAAACACTTGAGTATGGTTTTATTGA
TGAAATCATGGCCAACAACTCTTTGAGCTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A0F2E4Z4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	94.388	100	0.944
clpP	Streptococcus pneumoniae R6	94.388	100	0.944
clpP	Streptococcus pneumoniae TIGR4	94.388	100	0.944
clpP	Streptococcus pneumoniae D39	94.388	100	0.944
clpP	Streptococcus pyogenes JRS4	92.821	99.49	0.923
clpP	Streptococcus pyogenes MGAS315	92.821	99.49	0.923
clpP	Streptococcus thermophilus LMD-9	91.795	99.49	0.913
clpP	Streptococcus thermophilus LMG 18311	91.795	99.49	0.913
clpP	Streptococcus mutans UA159	89.231	99.49	0.888
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.179	99.49	0.867
clpP	Lactococcus lactis subsp. cremoris KW2	86.667	99.49	0.862
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571
clpP	Bacillus subtilis subsp. subtilis str. 168	57.292	97.959	0.561