Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   STO1_RS02990 Genome accession   NZ_AP018338
Coordinates   596467..597057 (+) Length   196 a.a.
NCBI ID   WP_061588314.1    Uniprot ID   A0A1X1FTX6
Organism   Streptococcus oralis subsp. tigurinus strain osk_001     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 593562..609182 596467..597057 within 0


Gene organization within MGE regions


Location: 593562..609182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STO1_RS02970 (STO1_005820) - 593562..594407 (-) 846 WP_096421899.1 DegV family protein -
  STO1_RS02975 (STO1_005830) - 594532..595089 (+) 558 WP_084939178.1 TetR/AcrR family transcriptional regulator -
  STO1_RS02980 (STO1_005840) - 595108..595575 (+) 468 WP_000136989.1 deoxycytidylate deaminase -
  STO1_RS02985 (STO1_005850) upp 595664..596293 (+) 630 WP_084939177.1 uracil phosphoribosyltransferase -
  STO1_RS02990 (STO1_005860) clpP 596467..597057 (+) 591 WP_061588314.1 ATP-dependent Clp protease proteolytic subunit Regulator
  STO1_RS03000 (STO1_005870) - 597136..597405 (+) 270 WP_000462130.1 YlbG family protein -
  STO1_RS03005 (STO1_005880) - 597494..598654 (+) 1161 WP_061588313.1 ABC transporter substrate-binding protein -
  STO1_RS03010 (STO1_005890) - 598775..599644 (+) 870 WP_061588312.1 branched-chain amino acid ABC transporter permease -
  STO1_RS03015 (STO1_005900) - 599648..600604 (+) 957 WP_000856263.1 branched-chain amino acid ABC transporter permease -
  STO1_RS03020 (STO1_005910) - 600604..601368 (+) 765 WP_001186016.1 ABC transporter ATP-binding protein -
  STO1_RS03025 (STO1_005920) - 601368..602078 (+) 711 WP_033584957.1 ABC transporter ATP-binding protein -
  STO1_RS03030 (STO1_005930) - 602419..603075 (+) 657 WP_000268646.1 CBS domain-containing protein -
  STO1_RS03040 (STO1_005940) prfB 603186..604281 (+) 1096 WP_096421901.1 peptide chain release factor 2 -
  STO1_RS03045 (STO1_005950) ftsE 604299..604991 (+) 693 WP_000022271.1 cell division ATP-binding protein FtsE -
  STO1_RS03050 (STO1_005960) ftsX 604984..605910 (+) 927 WP_000625557.1 permease-like cell division protein FtsX -
  STO1_RS03055 (STO1_005970) - 606129..608315 (+) 2187 WP_096421903.1 PTS transporter subunit IIBC -
  STO1_RS03060 (STO1_005980) - 608367..609182 (+) 816 WP_096421905.1 endonuclease/exonuclease/phosphatase family protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21474.54 Da        Isoelectric Point: 4.4829

>NTDB_id=69052 STO1_RS02990 WP_061588314.1 596467..597057(+) (clpP) [Streptococcus oralis subsp. tigurinus strain osk_001]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIRADVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILADNSGK
TVEQIHVDAERDYWMSAQETLEYGFIDEIMVNNSLS

Nucleotide


Download         Length: 591 bp        

>NTDB_id=69052 STO1_RS02990 WP_061588314.1 596467..597057(+) (clpP) [Streptococcus oralis subsp. tigurinus strain osk_001]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTATGATATTTACTCACGTTTACTAAAAGATCGTAT
CATCATGTTGACTGGACCAGTTGAAGACAACATGGCCAACTCCGTTATCGCCCAATTGCTCTTCTTGGATGCCCAAGACA
GTACAAAAGATATTTACCTTTATGTAAATACTCCGGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAGGGCAGATGTCCAAACCATCGTGATGGGGATGGCGGCCTCAATGGGGACTATCATTGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAAA
CCGATATGGCAATCGCTGCAGAGCACTTGCTTAAAACTCGTAAGACTTTGGAGCAAATTCTTGCAGATAACTCTGGTAAA
ACAGTTGAGCAAATTCATGTAGACGCAGAACGTGATTACTGGATGAGCGCCCAAGAAACACTTGAGTATGGTTTTATTGA
TGAAATCATGGTCAACAATTCTTTGAGCTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1FTX6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

92.857

100

0.929
  clpP Streptococcus pneumoniae R6

92.857

100

0.929
  clpP Streptococcus pneumoniae TIGR4

92.857

100

0.929
  clpP Streptococcus pneumoniae D39

92.857

100

0.929
  clpP Streptococcus pyogenes JRS4

91.327

100

0.913
  clpP Streptococcus pyogenes MGAS315

91.327

100

0.913
  clpP Streptococcus thermophilus LMD-9

91.795

99.49

0.913
  clpP Streptococcus thermophilus LMG 18311

91.795

99.49

0.913
  clpP Streptococcus mutans UA159

89.231

99.49

0.888
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.179

99.49

0.867
  clpP Lactococcus lactis subsp. cremoris KW2

86.667

99.49

0.862
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.421

96.939

0.566
  clpP Bacillus subtilis subsp. subtilis str. 168

56.771

97.959

0.556

Multiple sequence alignment