Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   M8286_RS03010 Genome accession   NZ_CP097577
Coordinates   607214..607918 (+) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain 3112     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 602214..612918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS02985 (M8286_03005) - 603112..603975 (+) 864 WP_275601429.1 hypothetical protein -
  M8286_RS02990 (M8286_03010) - 604022..604681 (-) 660 WP_275601430.1 amino acid ABC transporter permease -
  M8286_RS02995 (M8286_03015) - 604696..605394 (-) 699 WP_275601431.1 amino acid ABC transporter permease -
  M8286_RS03000 (M8286_03020) - 605409..606248 (-) 840 WP_275601432.1 transporter substrate-binding domain-containing protein -
  M8286_RS03005 (M8286_03025) - 606259..607020 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  M8286_RS03010 (M8286_03030) micA 607214..607918 (+) 705 WP_004298854.1 response regulator YycF Regulator
  M8286_RS03015 (M8286_03035) micB 607911..609260 (+) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  M8286_RS03020 (M8286_03040) vicX 609267..610070 (+) 804 WP_024407014.1 MBL fold metallo-hydrolase Regulator
  M8286_RS03025 (M8286_03045) pbp2b 610605..612680 (+) 2076 WP_275601433.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=690328 M8286_RS03010 WP_004298854.1 607214..607918(+) (micA) [Streptococcus suis strain 3112]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=690328 M8286_RS03010 WP_004298854.1 607214..607918(+) (micA) [Streptococcus suis strain 3112]
ATGAAAAAAATATTGATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTAATGCTATCTGCT
AAAGATAGTGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGTGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTAGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGCTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376