Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   M8286_RS03015 Genome accession   NZ_CP097577
Coordinates   607911..609260 (+) Length   449 a.a.
NCBI ID   WP_024379730.1    Uniprot ID   A0A0Z8J8V5
Organism   Streptococcus suis strain 3112     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 602911..614260
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS02985 (M8286_03005) - 603112..603975 (+) 864 WP_275601429.1 hypothetical protein -
  M8286_RS02990 (M8286_03010) - 604022..604681 (-) 660 WP_275601430.1 amino acid ABC transporter permease -
  M8286_RS02995 (M8286_03015) - 604696..605394 (-) 699 WP_275601431.1 amino acid ABC transporter permease -
  M8286_RS03000 (M8286_03020) - 605409..606248 (-) 840 WP_275601432.1 transporter substrate-binding domain-containing protein -
  M8286_RS03005 (M8286_03025) - 606259..607020 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  M8286_RS03010 (M8286_03030) micA 607214..607918 (+) 705 WP_004298854.1 response regulator YycF Regulator
  M8286_RS03015 (M8286_03035) micB 607911..609260 (+) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  M8286_RS03020 (M8286_03040) vicX 609267..610070 (+) 804 WP_024407014.1 MBL fold metallo-hydrolase Regulator
  M8286_RS03025 (M8286_03045) pbp2b 610605..612680 (+) 2076 WP_275601433.1 penicillin-binding protein PBP2B -
  M8286_RS03030 (M8286_03050) recR 612689..613285 (+) 597 WP_002935848.1 recombination mediator RecR -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51035.09 Da        Isoelectric Point: 4.5202

>NTDB_id=690329 M8286_RS03015 WP_024379730.1 607911..609260(+) (micB) [Streptococcus suis strain 3112]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=690329 M8286_RS03015 WP_024379730.1 607911..609260(+) (micB) [Streptococcus suis strain 3112]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGATATGAGGGGAAGTCCTGAAATCACAGACATGGCTAATTCCCTCAATGATCTGTCGGAG
GTCATTCGCTTAACTCATGATAATTTAGAACAAGAAAAGACACGTCTGACTTCCATCCTGTCCTATATGAGCGACGGTGT
TATTGCGACAGACCGTATCGGACGGATCATTATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAACCCAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCAACGATTCGTAGTGAGAGTGG
TCTAATTTCTGGCTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCAGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTGAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTCTATCGCGTGGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8J8V5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635