Detailed information NTG0688025

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: M3N36_RS01735
• Genome accession: NZ_CP097251
• Coordinates: 335975..336565 (+)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X8T4H8
• Organism: Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 330975..341565

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M3N36_RS01720 (M3N36_01720)	-	331787..333232 (-)	1446	WP_002990934.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
M3N36_RS01725 (M3N36_01725)	-	333320..334954 (+)	1635	WP_030127149.1	polysaccharide biosynthesis protein	-
M3N36_RS01730 (M3N36_01730)	upp	335122..335751 (+)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
M3N36_RS01735 (M3N36_01735)	clpP	335975..336565 (+)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
M3N36_RS01740 (M3N36_01740)	-	337060..337353 (+)	294	WP_030127150.1	YlbG family protein	-
M3N36_RS01745 (M3N36_01745)	tmk	337584..338219 (+)	636	WP_002990917.1	dTMP kinase	-
M3N36_RS01750 (M3N36_01750)	-	338237..339112 (+)	876	WP_030127151.1	DNA polymerase III subunit delta'	-
M3N36_RS01755 (M3N36_01755)	-	339131..339370 (+)	240	WP_011017422.1	hypothetical protein	-
M3N36_RS01760 (M3N36_01760)	yabA	339775..340098 (+)	324	WP_002985838.1	DNA replication initiation control protein YabA	-
M3N36_RS01765 (M3N36_01765)	rsmI	340103..340966 (+)	864	WP_030127152.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
M3N36_RS01770 (M3N36_01770)	-	340993..341385 (+)	393	WP_002985833.1	DUF5684 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=688025 M3N36_RS01735 WP_002985850.1 335975..336565(+) (clpP) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=688025 M3N36_RS01735 WP_002985850.1 335975..336565(+) (clpP) [Streptococcus pyogenes strain 21SPY7071 isolate cerebral abscess]
ATGATTCCTGTCGTTATTGAACAAACTAGTCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACTAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA
ACGATTAAACAAATCCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAACAACGAACTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561