Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   KK0981_RS10540 Genome accession   NZ_AP017971
Coordinates   1945234..1946250 (-) Length   338 a.a.
NCBI ID   WP_075218762.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain KK0981     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1940234..1951250
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KK0981_RS12635 - 1940311..1940442 (-) 132 WP_000768904.1 hypothetical protein -
  KK0981_RS10500 (KK0981_40500) - 1940443..1941633 (-) 1191 WP_000167769.1 acetate kinase -
  KK0981_RS10505 (KK0981_40510) comYH 1941684..1942637 (-) 954 WP_000345137.1 class I SAM-dependent methyltransferase Machinery gene
  KK0981_RS10510 - 1942698..1943292 (-) 595 Protein_1955 class I SAM-dependent methyltransferase -
  KK0981_RS10515 (KK0981_40540) comGG/cglG 1943429..1943842 (-) 414 WP_000265623.1 competence type IV pilus minor pilin ComGG Machinery gene
  KK0981_RS10520 (KK0981_40550) comGF/cglF 1943820..1944281 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  KK0981_RS10525 (KK0981_40560) comGE/cglE 1944244..1944546 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  KK0981_RS10530 (KK0981_40570) comGD/cglD 1944509..1944913 (-) 405 WP_000588026.1 competence type IV pilus minor pilin ComGD Machinery gene
  KK0981_RS10535 (KK0981_40580) comGC/cglC 1944906..1945232 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  KK0981_RS10540 (KK0981_40590) comGB/cglB 1945234..1946250 (-) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  KK0981_RS10545 (KK0981_40600) comGA/cglA/cilD 1946198..1947139 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  KK0981_RS10550 (KK0981_40610) - 1947215..1947580 (-) 366 WP_000286415.1 DUF1033 family protein -
  KK0981_RS10555 (KK0981_40620) - 1947731..1948789 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  KK0981_RS10560 (KK0981_40630) nagA 1948952..1950103 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38478.51 Da        Isoelectric Point: 9.6073

>NTDB_id=68719 KK0981_RS10540 WP_075218762.1 1945234..1946250(-) (comGB/cglB) [Streptococcus pneumoniae strain KK0981]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVIQMRAGLSQGKSFSEMMESLGFSSTI
ITQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=68719 KK0981_RS10540 WP_075218762.1 1945234..1946250(-) (comGB/cglB) [Streptococcus pneumoniae strain KK0981]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGATCCAGATGCGTGCGGGCTTGTCTCAAGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATTTTCAAGCACCATT
ATCACTCAGTTATCCCTAGCTGAAGTTCATGGAAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCTAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCAAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAAATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae D39

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae R6

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae TIGR4

98.225

100

0.982
  comGB/cglB Streptococcus mitis SK321

94.97

100

0.95
  comGB/cglB Streptococcus mitis NCTC 12261

94.675

100

0.947
  comYB Streptococcus gordonii str. Challis substr. CH1

71.131

99.408

0.707
  comYB Streptococcus mutans UA140

57.862

94.083

0.544
  comYB Streptococcus mutans UA159

57.862

94.083

0.544
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment