Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   KK0981_RS10525 Genome accession   NZ_AP017971
Coordinates   1944244..1944546 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain KK0981     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1939244..1949546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KK0981_RS10495 (KK0981_40490) rnpA 1939923..1940294 (-) 372 WP_000739244.1 ribonuclease P protein component -
  KK0981_RS12635 - 1940311..1940442 (-) 132 WP_000768904.1 hypothetical protein -
  KK0981_RS10500 (KK0981_40500) - 1940443..1941633 (-) 1191 WP_000167769.1 acetate kinase -
  KK0981_RS10505 (KK0981_40510) comYH 1941684..1942637 (-) 954 WP_000345137.1 class I SAM-dependent methyltransferase Machinery gene
  KK0981_RS10510 - 1942698..1943292 (-) 595 Protein_1955 class I SAM-dependent methyltransferase -
  KK0981_RS10515 (KK0981_40540) comGG/cglG 1943429..1943842 (-) 414 WP_000265623.1 competence type IV pilus minor pilin ComGG Machinery gene
  KK0981_RS10520 (KK0981_40550) comGF/cglF 1943820..1944281 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  KK0981_RS10525 (KK0981_40560) comGE/cglE 1944244..1944546 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  KK0981_RS10530 (KK0981_40570) comGD/cglD 1944509..1944913 (-) 405 WP_000588026.1 competence type IV pilus minor pilin ComGD Machinery gene
  KK0981_RS10535 (KK0981_40580) comGC/cglC 1944906..1945232 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  KK0981_RS10540 (KK0981_40590) comGB/cglB 1945234..1946250 (-) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  KK0981_RS10545 (KK0981_40600) comGA/cglA/cilD 1946198..1947139 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  KK0981_RS10550 (KK0981_40610) - 1947215..1947580 (-) 366 WP_000286415.1 DUF1033 family protein -
  KK0981_RS10555 (KK0981_40620) - 1947731..1948789 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=68716 KK0981_RS10525 WP_000413382.1 1944244..1944546(-) (comGE/cglE) [Streptococcus pneumoniae strain KK0981]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=68716 KK0981_RS10525 WP_000413382.1 1944244..1944546(-) (comGE/cglE) [Streptococcus pneumoniae strain KK0981]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment